Enteroaggregative Escherichia coli: A review of trends, diagnosis, and treatment

David J. Cennimo; Hoonmo Koo; Jamal A. Mohamed; David B. Huang; Tom Chiang

Enteroaggregative Escherichia coli: A review of trends, diagnosis, and treatment

David J. Cennimo, Hoonmo Koo, Jamal A. Mohamed, David B. Huang, Tom Chiang

Research output: Contribution to journal › Review article › peer-review

Abstract

Enteroaggregative Escherichia coli (EAEC) is an increasingly recognized cause of acute diarrhea among both children and adults. Travelers to developing regions such as India, Jamaica, and Mexico are at increased risk. Contamination of food and water plays a central role in transmission. The clinical presentation of EAEC infection is characterized by watery diarrhea, usually unaccompanied by blood or mucus. The gold standard for diagnosis is the HEp-2 cell adherence assay; the unique "stacked-brick" aggregative pattern of adherence is characteristic of this pathogen. However, because laboratory diagnosis is not routinely available, symptomatic infections are usually treated empirically. In most regions, EAEC strains are susceptible to the fluoroquinolones and rifaximin.

Original language	English (US)
Pages (from-to)	100-110
Number of pages	11
Journal	Infections in Medicine
Volume	24
Issue number	3
State	Published - Mar 2007
Externally published	Yes

Keywords

Diarrhea
Enteroaggregative
Escherichia coli

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

Cite this

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abstract = "Enteroaggregative Escherichia coli (EAEC) is an increasingly recognized cause of acute diarrhea among both children and adults. Travelers to developing regions such as India, Jamaica, and Mexico are at increased risk. Contamination of food and water plays a central role in transmission. The clinical presentation of EAEC infection is characterized by watery diarrhea, usually unaccompanied by blood or mucus. The gold standard for diagnosis is the HEp-2 cell adherence assay; the unique {"}stacked-brick{"} aggregative pattern of adherence is characteristic of this pathogen. However, because laboratory diagnosis is not routinely available, symptomatic infections are usually treated empirically. In most regions, EAEC strains are susceptible to the fluoroquinolones and rifaximin.",

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AU - Cennimo, David J.

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AU - Huang, David B.

AU - Chiang, Tom

PY - 2007/3

Y1 - 2007/3

N2 - Enteroaggregative Escherichia coli (EAEC) is an increasingly recognized cause of acute diarrhea among both children and adults. Travelers to developing regions such as India, Jamaica, and Mexico are at increased risk. Contamination of food and water plays a central role in transmission. The clinical presentation of EAEC infection is characterized by watery diarrhea, usually unaccompanied by blood or mucus. The gold standard for diagnosis is the HEp-2 cell adherence assay; the unique "stacked-brick" aggregative pattern of adherence is characteristic of this pathogen. However, because laboratory diagnosis is not routinely available, symptomatic infections are usually treated empirically. In most regions, EAEC strains are susceptible to the fluoroquinolones and rifaximin.

AB - Enteroaggregative Escherichia coli (EAEC) is an increasingly recognized cause of acute diarrhea among both children and adults. Travelers to developing regions such as India, Jamaica, and Mexico are at increased risk. Contamination of food and water plays a central role in transmission. The clinical presentation of EAEC infection is characterized by watery diarrhea, usually unaccompanied by blood or mucus. The gold standard for diagnosis is the HEp-2 cell adherence assay; the unique "stacked-brick" aggregative pattern of adherence is characteristic of this pathogen. However, because laboratory diagnosis is not routinely available, symptomatic infections are usually treated empirically. In most regions, EAEC strains are susceptible to the fluoroquinolones and rifaximin.

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Enteroaggregative Escherichia coli: A review of trends, diagnosis, and treatment

Abstract

Keywords

ASJC Scopus subject areas

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