Epidemiologic trends in head and neck cancer and aids in diagnosis

Nadarajah Vigneswaran; Michelle D. Williams

doi:10.1016/j.coms.2014.01.001

Epidemiologic trends in head and neck cancer and aids in diagnosis

Nadarajah Vigneswaran, Michelle D. Williams

Pathology

Research output: Contribution to journal › Review article › peer-review

579 Scopus citations

Abstract

Head and neck squamous cell carcinoma is the sixth most common cancer worldwide predominately associated with tobacco use. Changing cause and increased incidence in oropharyngeal carcinomas is associated with high-risk types of human papilloma virus and has an improved survival. Optical devices may augment visual oral examination; however, their lack of specificity still warrants tissue evaluation/biopsy. Histologic factors of oral carcinomas are critical for patient management and prognostic determination. Clinical biomarkers are still needed to improve early detection, predict malignant transformation, and optimize therapies.

Original language	English (US)
Pages (from-to)	123-141
Number of pages	19
Journal	Oral and Maxillofacial Surgery Clinics of North America
Volume	26
Issue number	2
DOIs	https://doi.org/10.1016/j.coms.2014.01.001
State	Published - May 2014

Keywords

Diagnosis
Epidemiologic trends
Head and neck cancer
Squamous cell carcinomas

ASJC Scopus subject areas

Surgery
Oral Surgery
Otorhinolaryngology

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10.1016/j.coms.2014.01.001

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abstract = "Head and neck squamous cell carcinoma is the sixth most common cancer worldwide predominately associated with tobacco use. Changing cause and increased incidence in oropharyngeal carcinomas is associated with high-risk types of human papilloma virus and has an improved survival. Optical devices may augment visual oral examination; however, their lack of specificity still warrants tissue evaluation/biopsy. Histologic factors of oral carcinomas are critical for patient management and prognostic determination. Clinical biomarkers are still needed to improve early detection, predict malignant transformation, and optimize therapies.",

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AB - Head and neck squamous cell carcinoma is the sixth most common cancer worldwide predominately associated with tobacco use. Changing cause and increased incidence in oropharyngeal carcinomas is associated with high-risk types of human papilloma virus and has an improved survival. Optical devices may augment visual oral examination; however, their lack of specificity still warrants tissue evaluation/biopsy. Histologic factors of oral carcinomas are critical for patient management and prognostic determination. Clinical biomarkers are still needed to improve early detection, predict malignant transformation, and optimize therapies.

KW - Diagnosis

KW - Epidemiologic trends

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KW - Squamous cell carcinomas

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Epidemiologic trends in head and neck cancer and aids in diagnosis

Abstract

Keywords

ASJC Scopus subject areas

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