Epithelioid sarcoma. Flow cytometric study of dna content and regional dna heterogeneity

Adel K. El‐Naggar; Glenn M. Garcia

doi:10.1002/1097-0142(19920401)69:7<1721::AID-CNCR2820690713>3.0.CO;2-3

Epithelioid sarcoma. Flow cytometric study of dna content and regional dna heterogeneity

Adel K. El‐Naggar, Glenn M. Garcia

Pathology

Research output: Contribution to journal › Article › peer-review

17 Scopus citations

Abstract

The DNA content and regional DNA heterogeneity in correlation with clinicopathologic parameters and patient survival were investigated in epithelioid sarcoma. Such neoplasms preponderantly manifest diploid DNA content and a remarkably stable intratumoral and inter‐tumoral DNA content. Small tumor size (< 5.0 cm) and low S‐phase fraction (< 5%) were significant prognostic factors in this study. Ploidy status, mitotic rate, age, and postsurgical treatment were not significantly correlated with survival.

Original language	English (US)
Pages (from-to)	1721-1728
Number of pages	8
Journal	Cancer
Volume	69
Issue number	7
DOIs	https://doi.org/10.1002/1097-0142(19920401)69:7<1721::AID-CNCR2820690713>3.0.CO;2-3
State	Published - Apr 1 1992

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1002/1097-0142(19920401)69:7<1721::AID-CNCR2820690713>3.0.CO;2-3

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abstract = "The DNA content and regional DNA heterogeneity in correlation with clinicopathologic parameters and patient survival were investigated in epithelioid sarcoma. Such neoplasms preponderantly manifest diploid DNA content and a remarkably stable intratumoral and inter‐tumoral DNA content. Small tumor size (< 5.0 cm) and low S‐phase fraction (< 5%) were significant prognostic factors in this study. Ploidy status, mitotic rate, age, and postsurgical treatment were not significantly correlated with survival.",

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N2 - The DNA content and regional DNA heterogeneity in correlation with clinicopathologic parameters and patient survival were investigated in epithelioid sarcoma. Such neoplasms preponderantly manifest diploid DNA content and a remarkably stable intratumoral and inter‐tumoral DNA content. Small tumor size (< 5.0 cm) and low S‐phase fraction (< 5%) were significant prognostic factors in this study. Ploidy status, mitotic rate, age, and postsurgical treatment were not significantly correlated with survival.

AB - The DNA content and regional DNA heterogeneity in correlation with clinicopathologic parameters and patient survival were investigated in epithelioid sarcoma. Such neoplasms preponderantly manifest diploid DNA content and a remarkably stable intratumoral and inter‐tumoral DNA content. Small tumor size (< 5.0 cm) and low S‐phase fraction (< 5%) were significant prognostic factors in this study. Ploidy status, mitotic rate, age, and postsurgical treatment were not significantly correlated with survival.

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Epithelioid sarcoma. Flow cytometric study of dna content and regional dna heterogeneity

Abstract

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