TY - JOUR
T1 - Estrogen replacement therapy following treatment for stage I endometrial carcinoma
AU - Lee, Roger B.
AU - Burke, Thomas W.
AU - Park, Robert C.
N1 - Copyright:
Copyright 2014 Elsevier B.V., All rights reserved.
PY - 1990/2
Y1 - 1990/2
N2 - One hundred forty-four patients with clinical stage I endometrial adenocarcinoma were treated over an 11-year period at Madigan Army Medical Center and Brooke Army Medical Center. Following surgical staging, 44 selected patients were placed on oral estrogen replacement for a median duration of 64 months. In the estrogen user group, there were no recurrent endometrial cancer and no intercurrent death. Of the 99 nonestrogen users, there were 8 recurrences (8%) and 8 intercurrent deaths. Patients placed on estrogen replacement had low-risk factors for recurrence, namely, low tumor grade (grades 1 and 2), less than 1 2 myometrial invasion, and no metastases to lymph nodes or other organs. Postoperative estrogen replacement appears to be safe in selected low-risk patients.
AB - One hundred forty-four patients with clinical stage I endometrial adenocarcinoma were treated over an 11-year period at Madigan Army Medical Center and Brooke Army Medical Center. Following surgical staging, 44 selected patients were placed on oral estrogen replacement for a median duration of 64 months. In the estrogen user group, there were no recurrent endometrial cancer and no intercurrent death. Of the 99 nonestrogen users, there were 8 recurrences (8%) and 8 intercurrent deaths. Patients placed on estrogen replacement had low-risk factors for recurrence, namely, low tumor grade (grades 1 and 2), less than 1 2 myometrial invasion, and no metastases to lymph nodes or other organs. Postoperative estrogen replacement appears to be safe in selected low-risk patients.
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U2 - 10.1016/0090-8258(90)90171-G
DO - 10.1016/0090-8258(90)90171-G
M3 - Article
C2 - 2298408
AN - SCOPUS:0025162119
SN - 0090-8258
VL - 36
SP - 189
EP - 191
JO - Gynecologic oncology
JF - Gynecologic oncology
IS - 2
ER -