Ethambutol: Friend or foe?

Rosa A. Tang; Jade Schiffman; Roberto Alejandro Cruz; Gabriela Corsi

doi:10.1586/17469899.2014.898564

Ethambutol: Friend or foe?

Rosa A. Tang, Jade Schiffman, Roberto Alejandro Cruz, Gabriela Corsi

Head & Neck Surgery

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

Ethambutol (EMB) is one of the first-line antimycobacterial drugs used to treat tuberculosis and is also used to treat atypical mycobacterium infections. It is almost always used in combination with other antimycobacterial drugs. Ever since the drug's introduction in the 1960s, there have been descriptions of optic neuropathy associated with EMB. Despite a clear association of EMB-induced optic neuropathy, many questions remain unanswered, namely, which tests are more accurate to monitor toxicity, how often should they be performed and once the optic neuropathy is present, how much of it is reversible?

Original language	English (US)
Pages (from-to)	59-61
Number of pages	3
Journal	Expert Review of Ophthalmology
Volume	9
Issue number	2
DOIs	https://doi.org/10.1586/17469899.2014.898564
State	Published - Apr 2014

Keywords

Antimycobacterial drugs
Ethambutol
Ethambutol-induced optic neuropathy
Mycobacterium
Optic neuropathy

ASJC Scopus subject areas

Biomedical Engineering
Ophthalmology
Optometry

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title = "Ethambutol: Friend or foe?",

abstract = "Ethambutol (EMB) is one of the first-line antimycobacterial drugs used to treat tuberculosis and is also used to treat atypical mycobacterium infections. It is almost always used in combination with other antimycobacterial drugs. Ever since the drug's introduction in the 1960s, there have been descriptions of optic neuropathy associated with EMB. Despite a clear association of EMB-induced optic neuropathy, many questions remain unanswered, namely, which tests are more accurate to monitor toxicity, how often should they be performed and once the optic neuropathy is present, how much of it is reversible?",

keywords = "Antimycobacterial drugs, Ethambutol, Ethambutol-induced optic neuropathy, Mycobacterium, Optic neuropathy",

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T2 - Friend or foe?

AU - Tang, Rosa A.

AU - Schiffman, Jade

AU - Cruz, Roberto Alejandro

AU - Corsi, Gabriela

PY - 2014/4

Y1 - 2014/4

N2 - Ethambutol (EMB) is one of the first-line antimycobacterial drugs used to treat tuberculosis and is also used to treat atypical mycobacterium infections. It is almost always used in combination with other antimycobacterial drugs. Ever since the drug's introduction in the 1960s, there have been descriptions of optic neuropathy associated with EMB. Despite a clear association of EMB-induced optic neuropathy, many questions remain unanswered, namely, which tests are more accurate to monitor toxicity, how often should they be performed and once the optic neuropathy is present, how much of it is reversible?

AB - Ethambutol (EMB) is one of the first-line antimycobacterial drugs used to treat tuberculosis and is also used to treat atypical mycobacterium infections. It is almost always used in combination with other antimycobacterial drugs. Ever since the drug's introduction in the 1960s, there have been descriptions of optic neuropathy associated with EMB. Despite a clear association of EMB-induced optic neuropathy, many questions remain unanswered, namely, which tests are more accurate to monitor toxicity, how often should they be performed and once the optic neuropathy is present, how much of it is reversible?

KW - Antimycobacterial drugs

KW - Ethambutol

KW - Ethambutol-induced optic neuropathy

KW - Mycobacterium

KW - Optic neuropathy

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Ethambutol: Friend or foe?

Abstract

Keywords

ASJC Scopus subject areas

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