TY - JOUR
T1 - Evolution of genetic techniques
T2 - Past, present, and beyond
AU - Durmaz, Asude Alpman
AU - Karaca, Emin
AU - Demkow, Urszula
AU - Toruner, Gokce
AU - Schoumans, Jacqueline
AU - Cogulu, Ozgur
N1 - Publisher Copyright:
© 2015 Asude Alpman Durmaz et al.
PY - 2015
Y1 - 2015
N2 - Genetics is the study of heredity, which means the study of genes and factors related to all aspects of genes. The scientific history of genetics began with the works of Gregor Mendel in the mid-19th century. Prior to Mendel, genetics was primarily theoretical whilst, after Mendel, the science of genetics was broadened to include experimental genetics. Developments in all fields of genetics and genetic technology in the first half of the 20th century provided a basis for the later developments. In the second half of the 20th century, the molecular background of genetics has become more understandable. Rapid technological advancements, followed by the completion of Human Genome Project, have contributed a great deal to the knowledge of genetic factors and their impact on human life and diseases. Currently, more than 1800 disease genes have been identified, more than 2000 genetic tests have become available, and in conjunction with this at least 350 biotechnology-based products have been released onto the market. Novel technologies, particularly next generation sequencing, have dramatically accelerated the pace of biological research, while at the same time increasing expectations. In this paper, a brief summary of genetic history with short explanations of most popular genetic techniques is given.
AB - Genetics is the study of heredity, which means the study of genes and factors related to all aspects of genes. The scientific history of genetics began with the works of Gregor Mendel in the mid-19th century. Prior to Mendel, genetics was primarily theoretical whilst, after Mendel, the science of genetics was broadened to include experimental genetics. Developments in all fields of genetics and genetic technology in the first half of the 20th century provided a basis for the later developments. In the second half of the 20th century, the molecular background of genetics has become more understandable. Rapid technological advancements, followed by the completion of Human Genome Project, have contributed a great deal to the knowledge of genetic factors and their impact on human life and diseases. Currently, more than 1800 disease genes have been identified, more than 2000 genetic tests have become available, and in conjunction with this at least 350 biotechnology-based products have been released onto the market. Novel technologies, particularly next generation sequencing, have dramatically accelerated the pace of biological research, while at the same time increasing expectations. In this paper, a brief summary of genetic history with short explanations of most popular genetic techniques is given.
UR - http://www.scopus.com/inward/record.url?scp=84927127792&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84927127792&partnerID=8YFLogxK
U2 - 10.1155/2015/461524
DO - 10.1155/2015/461524
M3 - Review article
C2 - 25874212
AN - SCOPUS:84927127792
SN - 2314-6133
VL - 2015
JO - BioMed research international
JF - BioMed research international
M1 - 461524
ER -