TY - GEN
T1 - Expectation maximization reconstruction of PET image with non-rigid motion compensation
AU - Qiao, Feng
AU - Clark, John W.
AU - Pan, Tinsu
AU - Mawlawi, Osama
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2005
Y1 - 2005
N2 - Motion artifact degrades PET imaging which often leads to inaccurate quantification of radioactivity concentration. Current motion correction algorithms generally lack the ability to compensate for non-rigid motions as well as perform poorly for frequent non-cyclical motions. In this paper, we derive from first principles a general list mode reconstruction algorithm that accounts for time-varying system responses. We further model the system response function in a way to incorporate the non-rigid motion. The resultant list mode reconstruction algorithm has the ability to compensate for frequent and non-rigid motions, with all detected events utilized. We also provide a histogram reconstruction algorithm that is tailored for gated PET acquisition with reduced usage of computational resource. This algorithm shows good motion compensation capability with computer simulated data and there is no obvious motion artifact visible on the reconstructed image.
AB - Motion artifact degrades PET imaging which often leads to inaccurate quantification of radioactivity concentration. Current motion correction algorithms generally lack the ability to compensate for non-rigid motions as well as perform poorly for frequent non-cyclical motions. In this paper, we derive from first principles a general list mode reconstruction algorithm that accounts for time-varying system responses. We further model the system response function in a way to incorporate the non-rigid motion. The resultant list mode reconstruction algorithm has the ability to compensate for frequent and non-rigid motions, with all detected events utilized. We also provide a histogram reconstruction algorithm that is tailored for gated PET acquisition with reduced usage of computational resource. This algorithm shows good motion compensation capability with computer simulated data and there is no obvious motion artifact visible on the reconstructed image.
UR - http://www.scopus.com/inward/record.url?scp=33846895941&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=33846895941&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:33846895941
SN - 0780387406
SN - 9780780387409
T3 - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
SP - 4453
EP - 4456
BT - Proceedings of the 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
T2 - 2005 27th Annual International Conference of the Engineering in Medicine and Biology Society, IEEE-EMBS 2005
Y2 - 1 September 2005 through 4 September 2005
ER -