TY - JOUR
T1 - Exploiting molecular targets in pancreatic cancer
AU - Wolff, Robert A.
N1 - Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2002
Y1 - 2002
N2 - Oncology has entered an era of molecular therapy. Given the multitude of molecular defects involved with pancreatic carcinogenesis, invasion, and mestastasis, it is unlikely that single-agent targeted therapy will alter the course of this disease. Given the emergence of molecular targets and a growing number of agents available for clinical development, however, meaningful improvements in patient outcomes are expected, particularly if treatments are designed and delivered rationally.
AB - Oncology has entered an era of molecular therapy. Given the multitude of molecular defects involved with pancreatic carcinogenesis, invasion, and mestastasis, it is unlikely that single-agent targeted therapy will alter the course of this disease. Given the emergence of molecular targets and a growing number of agents available for clinical development, however, meaningful improvements in patient outcomes are expected, particularly if treatments are designed and delivered rationally.
UR - http://www.scopus.com/inward/record.url?scp=0036262402&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036262402&partnerID=8YFLogxK
U2 - 10.1016/S0889-8588(01)00012-0
DO - 10.1016/S0889-8588(01)00012-0
M3 - Review article
C2 - 12063824
AN - SCOPUS:0036262402
SN - 0889-8588
VL - 16
SP - 139
EP - 157
JO - Hematology/Oncology Clinics of North America
JF - Hematology/Oncology Clinics of North America
IS - 1
ER -