Exploring the Advantages and Challenges of MR-Guided Radiotherapy in Non–Small-Cell Lung Cancer: Who are the Optimal Candidates?

Trudy C. Wu; Lauren M. Smith; David Woolf; Corinne Faivre-Finn; Percy Lee

doi:10.1016/j.semradonc.2023.10.007

Exploring the Advantages and Challenges of MR-Guided Radiotherapy in Non–Small-Cell Lung Cancer: Who are the Optimal Candidates?

Trudy C. Wu, Lauren M. Smith, David Woolf, Corinne Faivre-Finn, Percy Lee

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

The landscape of lung radiotherapy (RT) has rapidly evolved over the past decade with modern RT and surgical techniques, systemic therapies, and expanding indications for RT. To date, 2 MRI-guided RT (MRgRT) units, 1 using a 0.35T magnet and 1 using a 1.5T magnet, are available for commercial use with more systems in the pipeline. MRgRT offers distinct advantages such as real-time target tracking, margin reduction, and on-table treatment adaptation, which may help overcome many of the common challenges associated with thoracic RT. Nonetheless, the use of MRI for image guidance and the current MRgRT units also have intrinsic limitations. In this review article, we will discuss clinical experiences to date, advantages, challenges, and future directions of MRgRT to the lung.

Original language	English (US)
Pages (from-to)	56-63
Number of pages	8
Journal	Seminars in radiation oncology
Volume	34
Issue number	1
DOIs	https://doi.org/10.1016/j.semradonc.2023.10.007
State	Published - Jan 2024
Externally published	Yes

ASJC Scopus subject areas

Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

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10.1016/j.semradonc.2023.10.007

Cite this

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title = "Exploring the Advantages and Challenges of MR-Guided Radiotherapy in Non–Small-Cell Lung Cancer: Who are the Optimal Candidates?",

abstract = "The landscape of lung radiotherapy (RT) has rapidly evolved over the past decade with modern RT and surgical techniques, systemic therapies, and expanding indications for RT. To date, 2 MRI-guided RT (MRgRT) units, 1 using a 0.35T magnet and 1 using a 1.5T magnet, are available for commercial use with more systems in the pipeline. MRgRT offers distinct advantages such as real-time target tracking, margin reduction, and on-table treatment adaptation, which may help overcome many of the common challenges associated with thoracic RT. Nonetheless, the use of MRI for image guidance and the current MRgRT units also have intrinsic limitations. In this review article, we will discuss clinical experiences to date, advantages, challenges, and future directions of MRgRT to the lung.",

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AB - The landscape of lung radiotherapy (RT) has rapidly evolved over the past decade with modern RT and surgical techniques, systemic therapies, and expanding indications for RT. To date, 2 MRI-guided RT (MRgRT) units, 1 using a 0.35T magnet and 1 using a 1.5T magnet, are available for commercial use with more systems in the pipeline. MRgRT offers distinct advantages such as real-time target tracking, margin reduction, and on-table treatment adaptation, which may help overcome many of the common challenges associated with thoracic RT. Nonetheless, the use of MRI for image guidance and the current MRgRT units also have intrinsic limitations. In this review article, we will discuss clinical experiences to date, advantages, challenges, and future directions of MRgRT to the lung.

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Exploring the Advantages and Challenges of MR-Guided Radiotherapy in Non–Small-Cell Lung Cancer: Who are the Optimal Candidates?

Abstract

ASJC Scopus subject areas

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