TY - JOUR
T1 - Exploring the Association Between Elevated Body Mass Index and Barrett's Esophagus
T2 - A Systematic Review and Meta-Analysis
AU - Kamat, Paresh
AU - Wen, Sijin
AU - Morris, Jeffrey
AU - Anandasabapathy, Sharmila
PY - 2009/2
Y1 - 2009/2
N2 - We performed a systematic review and meta-analysis to study the association between elevated body mass index (BMI) and Barrett's esophagus (BE). Cross-sectional, case-control and cohort studies published through February 2008 that met strict inclusion and exclusion criteria were included. Summary estimates were calculated for the association between BE and being either overweight (BMI ≥ 25 kg/m2) or obese (BMI ≥ 30 kg/m2), or both. Based on 11 studies included in this analysis, there was a statistically significant relationship between increasing BMI and BE. Further studies are needed to evaluate if the presence of reflux attenuates the strength of this relationship, and if a particular pattern of obesity is more strongly associated with BE.
AB - We performed a systematic review and meta-analysis to study the association between elevated body mass index (BMI) and Barrett's esophagus (BE). Cross-sectional, case-control and cohort studies published through February 2008 that met strict inclusion and exclusion criteria were included. Summary estimates were calculated for the association between BE and being either overweight (BMI ≥ 25 kg/m2) or obese (BMI ≥ 30 kg/m2), or both. Based on 11 studies included in this analysis, there was a statistically significant relationship between increasing BMI and BE. Further studies are needed to evaluate if the presence of reflux attenuates the strength of this relationship, and if a particular pattern of obesity is more strongly associated with BE.
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U2 - 10.1016/j.athoracsur.2008.08.003
DO - 10.1016/j.athoracsur.2008.08.003
M3 - Review article
C2 - 19161814
AN - SCOPUS:58249135670
SN - 0003-4975
VL - 87
SP - 655
EP - 662
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 2
ER -