TY - JOUR
T1 - Fast three-dimensional dual echo Dixon technique improves fat suppression in breast MRI
AU - Le-Petross, Huong
AU - Kundra, Vikas
AU - Szklaruk, Janio
AU - Wei, Wei
AU - Hortobagyi, Gabriel N.
AU - Ma, Jingfei
N1 - Copyright:
Copyright 2015 Elsevier B.V., All rights reserved.
PY - 2010/4
Y1 - 2010/4
N2 - Purpose: To compare qualitative and quantitative measures of the contrast-enhanced dual-echo Dixon technique with the commonly used standard three-dimensional (3D) gradient echo (spectrally selective fat suppression) technique (SS-FS) in breast MRI exams (bMRI). Materials and Methods: A total of 19 women, with prescheduled bMRI exam, were recruited to our study between 2006 and 2008. Dixon and standard SS-SF techniques were used on both breasts of each patient. Image quality was rated in five categories: fat suppression quality, fat suppression uniformity, lesion margin clarity, lesion visibility, and axillary visibility. For quantitative assessment, we calculated the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of lesion to breast, SNR ef.ciency, and CNR efficiency. Results: Of 19 patients evaluated, 13 had a primary breast malignancy and 6 had benign lesions or negative exams. Dixon images were rated higher in four of five qualitative categories (P < 0.0001) and required a shorter scan time. Dixon images yielded significantly higher SNR (43.8) and CNR (40.1) values than did 3DGRE images (SNR = 34.8, CNR =25.3; P < 0.05). SNR efficiency (36.30) and CNR efficiency (33.79) values for Dixon images were also higher than were 3DGRE images (SNR efficiency =25.7, CNR efficiency = 19.1; P < 0.05). Conclusion: Dixon images were superior to the standard SS-SF images in both qualitative and quantitative assessment of 19 bMRI exams. The Dixon technique could replace standard SS-SF technique in bMRI exam, after our findings have been confirmed in future studies with a larger sample size.
AB - Purpose: To compare qualitative and quantitative measures of the contrast-enhanced dual-echo Dixon technique with the commonly used standard three-dimensional (3D) gradient echo (spectrally selective fat suppression) technique (SS-FS) in breast MRI exams (bMRI). Materials and Methods: A total of 19 women, with prescheduled bMRI exam, were recruited to our study between 2006 and 2008. Dixon and standard SS-SF techniques were used on both breasts of each patient. Image quality was rated in five categories: fat suppression quality, fat suppression uniformity, lesion margin clarity, lesion visibility, and axillary visibility. For quantitative assessment, we calculated the signal-to-noise ratio (SNR) and contrast-to-noise ratio (CNR) of lesion to breast, SNR ef.ciency, and CNR efficiency. Results: Of 19 patients evaluated, 13 had a primary breast malignancy and 6 had benign lesions or negative exams. Dixon images were rated higher in four of five qualitative categories (P < 0.0001) and required a shorter scan time. Dixon images yielded significantly higher SNR (43.8) and CNR (40.1) values than did 3DGRE images (SNR = 34.8, CNR =25.3; P < 0.05). SNR efficiency (36.30) and CNR efficiency (33.79) values for Dixon images were also higher than were 3DGRE images (SNR efficiency =25.7, CNR efficiency = 19.1; P < 0.05). Conclusion: Dixon images were superior to the standard SS-SF images in both qualitative and quantitative assessment of 19 bMRI exams. The Dixon technique could replace standard SS-SF technique in bMRI exam, after our findings have been confirmed in future studies with a larger sample size.
KW - Breast MRI
KW - Breast cancer
KW - Fast Dixon sequences
KW - Fat suppression
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U2 - 10.1002/jmri.22067
DO - 10.1002/jmri.22067
M3 - Article
C2 - 20373433
AN - SCOPUS:77950902005
SN - 1053-1807
VL - 31
SP - 889
EP - 894
JO - Journal of Magnetic Resonance Imaging
JF - Journal of Magnetic Resonance Imaging
IS - 4
ER -