TY - JOUR
T1 - Fear of cancer recurrence in patients with localized renal cell carcinoma
AU - Bergerot, Cristiane Decat
AU - Battle, Dena
AU - Philip, Errol J.
AU - Bergerot, Paulo Gustavo
AU - Msaouel, Pavlos
AU - Smith, Allan
AU - Bamgboje, Adeola Esther
AU - Shuch, Brian
AU - Derweesh, Ithaar H.
AU - Jonasch, Eric
AU - Stern, Adam P.
AU - Pal, Sumanta K.
AU - Staehler, Michael
N1 - Publisher Copyright:
© 2020 by American Society of Clinical Oncology
PY - 2020/11
Y1 - 2020/11
N2 - PURPOSE Patients with cancer commonly report distress and fear of cancer recurrence (FCR) impacting quality of life and clinical outcomes. This study aims to test the association between emotional well-being and clinical characteristics of survivors with localized renal cell carcinoma (RCC). MATERIALS AND METHODS Survivors with localized RCC were invited to participate in this study through social media by the Kidney Cancer Research Alliance. Participants self-reported clinical characteristics, distress (Distress Thermometer), and FCR (Fear of Cancer Recurrence-7). Ordinal regression was used to test the association between emotional well-being and patient characteristics. RESULTS A total of 412 survivors were included in this analysis. Participants were mostly female (79.4%) and well educated (58.3%), with a median age of 54 years (range, 30-80 years) and median time since diagnosis of 17.5 months. More than one half were diagnosed with stage I disease (56.1%). Most patients (62.3%) had a clear understanding of their diagnosis. A high prevalence of moderate to severe distress (67.0%) and FCR (54.9%) was reported across all survivors of RCC. Higher FCR was associated with female gender, younger age, and lack of understanding of their diagnosis (P 5.001), whereas more recent diagnosis was associated with higher distress levels (P 5.01). CONCLUSION Our findings suggest that FCR is a common problem that is persistent after therapy and that certain individuals, including female and younger patients, may be at particular risk of experiencing clinically relevant FCR.
AB - PURPOSE Patients with cancer commonly report distress and fear of cancer recurrence (FCR) impacting quality of life and clinical outcomes. This study aims to test the association between emotional well-being and clinical characteristics of survivors with localized renal cell carcinoma (RCC). MATERIALS AND METHODS Survivors with localized RCC were invited to participate in this study through social media by the Kidney Cancer Research Alliance. Participants self-reported clinical characteristics, distress (Distress Thermometer), and FCR (Fear of Cancer Recurrence-7). Ordinal regression was used to test the association between emotional well-being and patient characteristics. RESULTS A total of 412 survivors were included in this analysis. Participants were mostly female (79.4%) and well educated (58.3%), with a median age of 54 years (range, 30-80 years) and median time since diagnosis of 17.5 months. More than one half were diagnosed with stage I disease (56.1%). Most patients (62.3%) had a clear understanding of their diagnosis. A high prevalence of moderate to severe distress (67.0%) and FCR (54.9%) was reported across all survivors of RCC. Higher FCR was associated with female gender, younger age, and lack of understanding of their diagnosis (P 5.001), whereas more recent diagnosis was associated with higher distress levels (P 5.01). CONCLUSION Our findings suggest that FCR is a common problem that is persistent after therapy and that certain individuals, including female and younger patients, may be at particular risk of experiencing clinically relevant FCR.
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U2 - 10.1200/OP.20.00105
DO - 10.1200/OP.20.00105
M3 - Article
C2 - 32955409
AN - SCOPUS:85096151947
SN - 2688-1527
VL - 16
SP - E1264-E1271
JO - JCO Oncology Practice
JF - JCO Oncology Practice
IS - 11
ER -