@article{0be188a330c343bdb37bfd921197123d,
title = "Ferroptosis vulnerability in FLT3-mutant leukemia",
abstract = "Resistance to FLT3 inhibition is a prevalent challenge in managing FLT3-mutant acute myeloid leukemia (AML). A recent study by Sabatier et al. discovered ferroptosis vulnerability in FLT3-mutant AML and they propose a promising therapeutic approach of combining FLT3 inhibitors with ferroptosis inducers for treating this type of cancer.",
keywords = "acute myeloid leukemia, fatty acid synthesis, ferroptosis, FLT3, lipid peroxidation",
author = "Hyemin Lee and Li Zhuang and Boyi Gan",
note = "Funding Information: Research in the laboratory of the authors has been supported by The University of Texas MD Anderson Cancer Center , National Institutes of Health grants R01CA181196 , R01CA244144 , R01CA247992 , R01CA269646 and U54CA274220 , and Cancer Prevention and Research Institute of Texas grants RP220258 and RP230072 (to B.G.), and by Cancer Center support (core) grant P30 CA016672 from the National Cancer Institute (to the University of Texas MD Anderson Cancer Center). Publisher Copyright: {\textcopyright} 2023 Elsevier Inc.",
year = "2023",
month = jul,
doi = "10.1016/j.trecan.2023.04.011",
language = "English (US)",
volume = "9",
pages = "524--525",
journal = "Trends in Cancer",
issn = "2405-8033",
publisher = "Cell Press",
number = "7",
}