TY - JOUR
T1 - Fertility-Sparing Treatment for Early-Stage Cervical, Ovarian, and Endometrial Malignancies
AU - Nitecki, Roni
AU - Woodard, Terri
AU - Rauh-Hain, J. Alejandro
PY - 2020/12/1
Y1 - 2020/12/1
N2 - Approximately 20% of gynecologic malignancies are diagnosed in reproductive-aged women, and standard-of-care surgical treatment often precludes future fertility. In early-stage disease, shared decision making about fertility-sparing medical and surgical approaches may give well-selected patients the opportunity to pursue their family-building goals without compromising long-term survival. Although future fertility is an important consideration for young women with cancer, rates of fertility-sparing procedures remain low. Moreover, because data on pregnancy rates and outcomes after fertility-sparing treatments are limited, it is challenging to counsel patients on realistic expectations. This review examines the critical oncologic outcomes of fertility-sparing approaches in early-stage gynecologic malignancies and highlights pregnancy outcomes in this population.
AB - Approximately 20% of gynecologic malignancies are diagnosed in reproductive-aged women, and standard-of-care surgical treatment often precludes future fertility. In early-stage disease, shared decision making about fertility-sparing medical and surgical approaches may give well-selected patients the opportunity to pursue their family-building goals without compromising long-term survival. Although future fertility is an important consideration for young women with cancer, rates of fertility-sparing procedures remain low. Moreover, because data on pregnancy rates and outcomes after fertility-sparing treatments are limited, it is challenging to counsel patients on realistic expectations. This review examines the critical oncologic outcomes of fertility-sparing approaches in early-stage gynecologic malignancies and highlights pregnancy outcomes in this population.
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U2 - 10.1097/AOG.0000000000004163
DO - 10.1097/AOG.0000000000004163
M3 - Review article
C2 - 33156194
AN - SCOPUS:85096508584
SN - 0029-7844
VL - 136
SP - 1157
EP - 1169
JO - Obstetrics and gynecology
JF - Obstetrics and gynecology
IS - 6
ER -