TY - JOUR
T1 - First year after head and neck cancer
T2 - Quality of life
AU - Gritz, Ellen R.
AU - Carmack, Cindy L.
AU - De Moor, Carl
AU - Coscarelli, Anne
AU - Schacherer, Christopher W.
AU - Meyers, Eric G.
AU - Abemayor, Elliot
PY - 1999/1
Y1 - 1999/1
N2 - Purpose: Treatment regimens for head and neck cancer patients profoundly affect several quality-of-life domains. Rehabilitative needs have been identified through cross-sectional analyses; however, few studies have prospectively assessed quality of life, included assessment of psychosocial variables, and identified predictors of long-term follow-up. Participants and Methods: The present study addresses these limitations through a prospective assessment of 105 patients with a newly diagnosed first primary squamous cell carcinoma of the oral cavity, pharynx, or larynx. Participants were enrolled onto a larger randomized controlled trial comparing a provider-delivered smoking cessation intervention with a usual-care-advice control condition. Participants completed a battery of self-report measures after diagnosis and before treatment and additional quality-of-life instruments at 1 and 12 months after initial smoking cessation advice. Results: Participants displayed improvements at i months in functional status (P = .006) and in the areas of eating, diet, and speech; however, the latter three represent areas of continued dysfunction, and the changes were not statistically significant. Despite these improvements, patients reported a decline in certain quality- of-life domains, including marital (P = .002) and sexual functioning (P = .017), as well as an increase in alcohol use (P < .001). Predictors of quality of life at 12 months included treatment type, the Vigor subscale of the Profile of Mood States instrument, and quality-of-life scores obtained 1 month after initial smoking cessation advice. Conclusion: Results reinforce the need for rehabilitation management through the integration of psychologic and behavioral interventions in medical follow-up.
AB - Purpose: Treatment regimens for head and neck cancer patients profoundly affect several quality-of-life domains. Rehabilitative needs have been identified through cross-sectional analyses; however, few studies have prospectively assessed quality of life, included assessment of psychosocial variables, and identified predictors of long-term follow-up. Participants and Methods: The present study addresses these limitations through a prospective assessment of 105 patients with a newly diagnosed first primary squamous cell carcinoma of the oral cavity, pharynx, or larynx. Participants were enrolled onto a larger randomized controlled trial comparing a provider-delivered smoking cessation intervention with a usual-care-advice control condition. Participants completed a battery of self-report measures after diagnosis and before treatment and additional quality-of-life instruments at 1 and 12 months after initial smoking cessation advice. Results: Participants displayed improvements at i months in functional status (P = .006) and in the areas of eating, diet, and speech; however, the latter three represent areas of continued dysfunction, and the changes were not statistically significant. Despite these improvements, patients reported a decline in certain quality- of-life domains, including marital (P = .002) and sexual functioning (P = .017), as well as an increase in alcohol use (P < .001). Predictors of quality of life at 12 months included treatment type, the Vigor subscale of the Profile of Mood States instrument, and quality-of-life scores obtained 1 month after initial smoking cessation advice. Conclusion: Results reinforce the need for rehabilitation management through the integration of psychologic and behavioral interventions in medical follow-up.
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U2 - 10.1200/jco.1999.17.1.352
DO - 10.1200/jco.1999.17.1.352
M3 - Article
C2 - 10458254
AN - SCOPUS:0032895070
SN - 0732-183X
VL - 17
SP - 352
EP - 360
JO - Journal of Clinical Oncology
JF - Journal of Clinical Oncology
IS - 1
ER -