Abstract
A statistical technique is given for fitting the linear-quadratic model to experimental quantal response multifraction data using the time of the response as the end-point. The analysis used is based on the Cox Proportional Hazards model. The technique is useful for late effects where the time of occurrence of the response is dose dependent. The technique is compared to logistic regression analysis and the advantages and disadvantages are discussed. Both methods are applied to a lung pneumonitis experiment and a kidney experiment.
Original language | English (US) |
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Pages (from-to) | 459-468 |
Number of pages | 10 |
Journal | International journal of radiation biology |
Volume | 52 |
Issue number | 3 |
DOIs | |
State | Published - 1987 |
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
- Radiology Nuclear Medicine and imaging