TY - JOUR
T1 - Focal takotsubo cardiomyopathy with high-dose interleukin-2 therapy for malignant melanoma
AU - Damodaran, Senthil
AU - Mrozek, Ewa
AU - Liebner, David
AU - Kendra, Kari
N1 - Publisher Copyright:
© JNCCN-Journal of the National Comprehensive Cancer Network.
PY - 2014/12/1
Y1 - 2014/12/1
N2 - High-dose interleukin-2 (IL-2) is an available treatment option for patients with metastatic melanoma or renal cell carcinoma, and is associated with sustained complete and partial responses in a subset of patients. IL-2, however, is not devoid of toxicities, most of which involve the cardiovascular system and manifest as hypotension, arrhythmias, and cardiomyopathy. This report describes an unusual presentation of takotsubo cardiomyopathy in a postmenopausal woman receiving high-dose IL-2 for metastatic melanoma.
AB - High-dose interleukin-2 (IL-2) is an available treatment option for patients with metastatic melanoma or renal cell carcinoma, and is associated with sustained complete and partial responses in a subset of patients. IL-2, however, is not devoid of toxicities, most of which involve the cardiovascular system and manifest as hypotension, arrhythmias, and cardiomyopathy. This report describes an unusual presentation of takotsubo cardiomyopathy in a postmenopausal woman receiving high-dose IL-2 for metastatic melanoma.
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U2 - 10.6004/jnccn.2014.0168
DO - 10.6004/jnccn.2014.0168
M3 - Article
C2 - 25505207
AN - SCOPUS:84918774206
SN - 1540-1405
VL - 12
SP - 1666
EP - 1670
JO - JNCCN Journal of the National Comprehensive Cancer Network
JF - JNCCN Journal of the National Comprehensive Cancer Network
IS - 12
ER -