TY - JOUR
T1 - Focal therapy for localized prostate cancer
T2 - Is there a 'middle ground' between active surveillance and definitive treatment?
AU - Demirel, Cihan H.
AU - Altok, Muammer
AU - Davis, John W.
N1 - Publisher Copyright:
© 2018 Wolters Kluwer Medknow Publications. All rights reserved.
PY - 2019/1/1
Y1 - 2019/1/1
N2 - In recent years, it has come a long way in the diagnosis, treatment, and follow-up of prostate cancer. Beside this, it was argued that definitive treatments could cause overtreatment, particularly in the very low, low, and favorable risk group. When alternative treatment and follow-up methods are being considered for this group of patients, active surveillance is seen as a good alternative for patients with very low and low-risk groups in this era. However, it has become necessary to find other alternatives for patients in the favorable risk group or patients who cannot adopt active follow-up. In the light of technological developments, the concept of focal therapy was introduced with the intensification of research to treat only the lesioned area instead of treating the entire organ for prostate lesions though there are not many publications about many of them yet. According to the initial results, it was understood that the results could be good if the appropriate focal therapy technique was applied to the appropriate patient. Thus, focal therapies have begun to find their 'middle ground' place between definitive therapies and active follow-up.
AB - In recent years, it has come a long way in the diagnosis, treatment, and follow-up of prostate cancer. Beside this, it was argued that definitive treatments could cause overtreatment, particularly in the very low, low, and favorable risk group. When alternative treatment and follow-up methods are being considered for this group of patients, active surveillance is seen as a good alternative for patients with very low and low-risk groups in this era. However, it has become necessary to find other alternatives for patients in the favorable risk group or patients who cannot adopt active follow-up. In the light of technological developments, the concept of focal therapy was introduced with the intensification of research to treat only the lesioned area instead of treating the entire organ for prostate lesions though there are not many publications about many of them yet. According to the initial results, it was understood that the results could be good if the appropriate focal therapy technique was applied to the appropriate patient. Thus, focal therapies have begun to find their 'middle ground' place between definitive therapies and active follow-up.
KW - focal therapy
KW - multiparametric magnetic resonance imaging
KW - prostate biopsy
KW - prostate cancer
KW - prostatic neoplasms
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U2 - 10.4103/aja.aja_64_18
DO - 10.4103/aja.aja_64_18
M3 - Review article
C2 - 30178774
AN - SCOPUS:85059845903
SN - 1008-682X
VL - 21
SP - 37
EP - 44
JO - Asian journal of andrology
JF - Asian journal of andrology
IS - 1
ER -