Four of a kind beats a pair

Shawn B. Bratton

doi:10.1038/nchembio.1000

Four of a kind beats a pair

Shawn B. Bratton

Epigenetics & Molecular Carcinogenesis

Research output: Contribution to journal › Short survey › peer-review

Abstract

The proapoptotic cysteine protease caspase-6 participates in the neuropathology of several diseases. Unlike the active dimeric form, the caspase-6 zymogen forms a unique tetramer that can be stabilized by allosteric inhibitors, which prevents caspase-6 activation.

Original language	English (US)
Pages (from-to)	606-607
Number of pages	2
Journal	Nature Chemical Biology
Volume	8
Issue number	7
DOIs	https://doi.org/10.1038/nchembio.1000
State	Published - Jul 2012

ASJC Scopus subject areas

Molecular Biology
Cell Biology

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10.1038/nchembio.1000

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Four of a kind beats a pair

Abstract

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