Function and molecular mechanism of tumor-targeted peptides for delivering therapeutic genes and chemical drugs

Ryan Craig; Shulin Li

doi:10.2174/138955706777698615

Function and molecular mechanism of tumor-targeted peptides for delivering therapeutic genes and chemical drugs

Ryan Craig, Shulin Li

Research output: Contribution to journal › Review article › peer-review

11 Scopus citations

Abstract

Tumor-targeted chemo- or gene-therapies is a new form of treatment which provides the benefits of reducing systemic toxicity, increasing the tolerance, and enhancing therapeutic efficacy. This review will discuss the discovery, function, application, and mechanism by which the short peptides (5-9) work for tumor-targeted gene or drug delivery.

Original language	English (US)
Pages (from-to)	757-764
Number of pages	8
Journal	Mini-Reviews in Medicinal Chemistry
Volume	6
Issue number	7
DOIs	https://doi.org/10.2174/138955706777698615
State	Published - Jul 2006
Externally published	Yes

Keywords

Adhesion molecule
Drug delivery
Gene delivery
Gene therapy
Peptide
Phage display
Tumor vessel
Tumor-targeting

ASJC Scopus subject areas

Molecular Medicine
Pharmacology
Drug Discovery
Cancer Research

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AB - Tumor-targeted chemo- or gene-therapies is a new form of treatment which provides the benefits of reducing systemic toxicity, increasing the tolerance, and enhancing therapeutic efficacy. This review will discuss the discovery, function, application, and mechanism by which the short peptides (5-9) work for tumor-targeted gene or drug delivery.

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KW - Gene delivery

KW - Gene therapy

KW - Peptide

KW - Phage display

KW - Tumor vessel

KW - Tumor-targeting

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Function and molecular mechanism of tumor-targeted peptides for delivering therapeutic genes and chemical drugs

Abstract

Keywords

ASJC Scopus subject areas

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