TY - JOUR
T1 - Functional magnetic resonance cholangiography enhanced with Gd-EOB-DTPA
T2 - Effect of liver function on biliary system visualization
AU - Feng, Shi Ting
AU - Wu, Ling
AU - Chan, Tao
AU - Cai, Huasong
AU - Luo, Yanji
AU - Zheng, Keguo
AU - Tang, Di
AU - Li, Zi Ping
PY - 2014/5
Y1 - 2014/5
N2 - Purpose To evaluate effect of liver function on biliary system visualization using gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance cholangiography (CE-MRC). Materials and Methods In all, 39 patients were divided into three groups according to their Child-Pugh classification: group A, Child-Pugh class A (23); group B, class B (11); and group C, class C (5). They underwent Gd-EOB-DTPA CE-MRC. Biliary system visualization was qualitatively rated on a 5-point scale. Relative signal intensity (RSI) of common bile duct (CBD) and liver was quantitatively measured. Laboratory findings and the Model of Endstage Liver Disease (MELD) score were recorded. Results Visualization ratings of CBD, left hepatic duct, right hepatic duct, segmental branches of intrahepatic ducts, cystic duct, and gallbladder of group A were: 3.61 ± 0.58, 2.87 ± 0.97, 2.96 ± 0.77, 1.17 ± 0.58, 3.04 ± 0.83, 3.00 ± 0.95, respectively; group B: 2.00 ± 0.61, 1.09 ± 0.64, 0.91 ± 0.54, 0.27 ± 0.13, 1.36 ± 0.62, 1.45 ± 0.54, respectively; group C: 1.40 ± 0.73, 1.00 ± 0.51, 1.00 ± 0.51, 0.00 ± 0.00, 0.60 ± 0.39, 0.60 ± 0.39, respectively. RSI of CBD of groups A to C were 17.12 ± 0.41, 3.95 ± 0.63, 3.33 ± 0.30, respectively. RSI of liver of groups A to C were 6.73 ± 0.72, 2.53 ± 1.02, 2.05 ± 0.11, respectively. CE-MRC images of group A were significantly better than those of group B and C in terms of both visualization ratings and RSI of CBD. CBD RSI positively correlated with liver RSI (r = 0.99, P < 0.001). The total serum bilirubin level and MELD score were significant predictors of RSI of CBD. Conclusion Different liver function according to Child-Pugh classification significantly affects biliary system visualization of Gd-EOB-DTPA CE-MRC. J. Magn. Reson. Imaging 2014;39:1254-1258. © 2013 Wiley Periodicals, Inc.
AB - Purpose To evaluate effect of liver function on biliary system visualization using gadolinium ethoxybenzyl diethylenetriamine pentaacetic acid (Gd-EOB-DTPA)-enhanced magnetic resonance cholangiography (CE-MRC). Materials and Methods In all, 39 patients were divided into three groups according to their Child-Pugh classification: group A, Child-Pugh class A (23); group B, class B (11); and group C, class C (5). They underwent Gd-EOB-DTPA CE-MRC. Biliary system visualization was qualitatively rated on a 5-point scale. Relative signal intensity (RSI) of common bile duct (CBD) and liver was quantitatively measured. Laboratory findings and the Model of Endstage Liver Disease (MELD) score were recorded. Results Visualization ratings of CBD, left hepatic duct, right hepatic duct, segmental branches of intrahepatic ducts, cystic duct, and gallbladder of group A were: 3.61 ± 0.58, 2.87 ± 0.97, 2.96 ± 0.77, 1.17 ± 0.58, 3.04 ± 0.83, 3.00 ± 0.95, respectively; group B: 2.00 ± 0.61, 1.09 ± 0.64, 0.91 ± 0.54, 0.27 ± 0.13, 1.36 ± 0.62, 1.45 ± 0.54, respectively; group C: 1.40 ± 0.73, 1.00 ± 0.51, 1.00 ± 0.51, 0.00 ± 0.00, 0.60 ± 0.39, 0.60 ± 0.39, respectively. RSI of CBD of groups A to C were 17.12 ± 0.41, 3.95 ± 0.63, 3.33 ± 0.30, respectively. RSI of liver of groups A to C were 6.73 ± 0.72, 2.53 ± 1.02, 2.05 ± 0.11, respectively. CE-MRC images of group A were significantly better than those of group B and C in terms of both visualization ratings and RSI of CBD. CBD RSI positively correlated with liver RSI (r = 0.99, P < 0.001). The total serum bilirubin level and MELD score were significant predictors of RSI of CBD. Conclusion Different liver function according to Child-Pugh classification significantly affects biliary system visualization of Gd-EOB-DTPA CE-MRC. J. Magn. Reson. Imaging 2014;39:1254-1258. © 2013 Wiley Periodicals, Inc.
KW - Child-Pugh classification
KW - Gd-EOB-DTPA
KW - magnetic resonance cholangiography
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U2 - 10.1002/jmri.24277
DO - 10.1002/jmri.24277
M3 - Article
C2 - 24115466
AN - SCOPUS:84898479528
SN - 1053-1807
VL - 39
SP - 1254
EP - 1258
JO - Journal of Magnetic Resonance Imaging
JF - Journal of Magnetic Resonance Imaging
IS - 5
ER -