Functioning acinar cell pancreatic carcinoma: Diagnosis on mangafodipir trisodium (Mn-DPDP)-enhanced MRI

Dushyant Sahani; Srinivasa R. Prasad; Michael Maher; Andrew L. Warshaw; Peter F. Hahn; Sanjay Saini

doi:10.1097/00004728-200201000-00019

Functioning acinar cell pancreatic carcinoma: Diagnosis on mangafodipir trisodium (Mn-DPDP)-enhanced MRI

Dushyant Sahani, Srinivasa R. Prasad, Michael Maher, Andrew L. Warshaw, Peter F. Hahn, Sanjay Saini

Research output: Contribution to journal › Article › peer-review

25 Scopus citations

Abstract

We describe the imaging findings of a functional pancreatic acinar cell carcinoma in a patient who presented with weight loss, hyperlipasemia and multiple foci of subcutaneous fat necrosis. The tumor invaded the adjacent splenic and portal vein, causing isolated left-sided portal hypertension. At MRI, the tumor showed marked enhancement following administration of the hepatobiliary-specific contrast agent mangafodipir trisodium (Mn-DPDP), thereby demonstrating the functional nature of the tumor. Avid uptake of Mn-DPDP by a functioning pancreatic tumor has not been reported in the radiology literature.

Original language	English (US)
Pages (from-to)	126-128
Number of pages	3
Journal	Journal of computer assisted tomography
Volume	26
Issue number	1
DOIs	https://doi.org/10.1097/00004728-200201000-00019
State	Published - 2002
Externally published	Yes

Keywords

Acinar cell - Magnetic resonance imaging
Carcinoma
Pancreas

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

Access to Document

10.1097/00004728-200201000-00019

Cite this

@article{2820fa7b144c4f4a8d63b014c514fe22,

title = "Functioning acinar cell pancreatic carcinoma: Diagnosis on mangafodipir trisodium (Mn-DPDP)-enhanced MRI",

abstract = "We describe the imaging findings of a functional pancreatic acinar cell carcinoma in a patient who presented with weight loss, hyperlipasemia and multiple foci of subcutaneous fat necrosis. The tumor invaded the adjacent splenic and portal vein, causing isolated left-sided portal hypertension. At MRI, the tumor showed marked enhancement following administration of the hepatobiliary-specific contrast agent mangafodipir trisodium (Mn-DPDP), thereby demonstrating the functional nature of the tumor. Avid uptake of Mn-DPDP by a functioning pancreatic tumor has not been reported in the radiology literature.",

keywords = "Acinar cell - Magnetic resonance imaging, Carcinoma, Pancreas",

author = "Dushyant Sahani and Prasad, {Srinivasa R.} and Michael Maher and Warshaw, {Andrew L.} and Hahn, {Peter F.} and Sanjay Saini",

year = "2002",

doi = "10.1097/00004728-200201000-00019",

language = "English (US)",

volume = "26",

pages = "126--128",

journal = "Journal of computer assisted tomography",

issn = "0363-8715",

publisher = "Lippincott Williams and Wilkins",

number = "1",

}

TY - JOUR

T1 - Functioning acinar cell pancreatic carcinoma

T2 - Diagnosis on mangafodipir trisodium (Mn-DPDP)-enhanced MRI

AU - Sahani, Dushyant

AU - Prasad, Srinivasa R.

AU - Maher, Michael

AU - Warshaw, Andrew L.

AU - Hahn, Peter F.

AU - Saini, Sanjay

PY - 2002

Y1 - 2002

N2 - We describe the imaging findings of a functional pancreatic acinar cell carcinoma in a patient who presented with weight loss, hyperlipasemia and multiple foci of subcutaneous fat necrosis. The tumor invaded the adjacent splenic and portal vein, causing isolated left-sided portal hypertension. At MRI, the tumor showed marked enhancement following administration of the hepatobiliary-specific contrast agent mangafodipir trisodium (Mn-DPDP), thereby demonstrating the functional nature of the tumor. Avid uptake of Mn-DPDP by a functioning pancreatic tumor has not been reported in the radiology literature.

AB - We describe the imaging findings of a functional pancreatic acinar cell carcinoma in a patient who presented with weight loss, hyperlipasemia and multiple foci of subcutaneous fat necrosis. The tumor invaded the adjacent splenic and portal vein, causing isolated left-sided portal hypertension. At MRI, the tumor showed marked enhancement following administration of the hepatobiliary-specific contrast agent mangafodipir trisodium (Mn-DPDP), thereby demonstrating the functional nature of the tumor. Avid uptake of Mn-DPDP by a functioning pancreatic tumor has not been reported in the radiology literature.

KW - Acinar cell - Magnetic resonance imaging

KW - Carcinoma

KW - Pancreas

UR - http://www.scopus.com/inward/record.url?scp=0036145849&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0036145849&partnerID=8YFLogxK

U2 - 10.1097/00004728-200201000-00019

DO - 10.1097/00004728-200201000-00019

M3 - Article

C2 - 11801915

AN - SCOPUS:0036145849

SN - 0363-8715

VL - 26

SP - 126

EP - 128

JO - Journal of computer assisted tomography

JF - Journal of computer assisted tomography

IS - 1

ER -

Functioning acinar cell pancreatic carcinoma: Diagnosis on mangafodipir trisodium (Mn-DPDP)-enhanced MRI

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this