Functioning acinar cell pancreatic carcinoma: Diagnosis on mangafodipir trisodium (Mn-DPDP)-enhanced MRI

Dushyant Sahani, Srinivasa Prasad, Michael Maher, Andrew L. Warshaw, Peter F. Hahn, Sanjay Saini

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

We describe the imaging findings of a functional pancreatic acinar cell carcinoma in a patient who presented with weight loss, hyperlipasemia and multiple foci of subcutaneous fat necrosis. The tumor invaded the adjacent splenic and portal vein, causing isolated left-sided portal hypertension. At MRI, the tumor showed marked enhancement following administration of the hepatobiliary-specific contrast agent mangafodipir trisodium (Mn-DPDP), thereby demonstrating the functional nature of the tumor. Avid uptake of Mn-DPDP by a functioning pancreatic tumor has not been reported in the radiology literature.

Original languageEnglish (US)
Pages (from-to)126-128
Number of pages3
JournalJournal of computer assisted tomography
Volume26
Issue number1
DOIs
StatePublished - Jan 29 2002

Fingerprint

Acinar Cell Carcinoma
Neoplasms
Splenic Vein
Fat Necrosis
Subcutaneous Fat
Portal Hypertension
Portal Vein
Radiology
Contrast Media
Weight Loss
N,N'-bis(pyridoxal-5-phosphate)ethylenediamine-N,N'-diacetic acid
Pancreatic Carcinoma

Keywords

  • Acinar cell - Magnetic resonance imaging
  • Carcinoma
  • Pancreas

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

Cite this

Functioning acinar cell pancreatic carcinoma : Diagnosis on mangafodipir trisodium (Mn-DPDP)-enhanced MRI. / Sahani, Dushyant; Prasad, Srinivasa; Maher, Michael; Warshaw, Andrew L.; Hahn, Peter F.; Saini, Sanjay.

In: Journal of computer assisted tomography, Vol. 26, No. 1, 29.01.2002, p. 126-128.

Research output: Contribution to journalArticle

Sahani, Dushyant ; Prasad, Srinivasa ; Maher, Michael ; Warshaw, Andrew L. ; Hahn, Peter F. ; Saini, Sanjay. / Functioning acinar cell pancreatic carcinoma : Diagnosis on mangafodipir trisodium (Mn-DPDP)-enhanced MRI. In: Journal of computer assisted tomography. 2002 ; Vol. 26, No. 1. pp. 126-128.
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