Abstract
This chapter discusses the rationale for proton therapy in the treatment of gastrointestinal malignancies. It then discusses currently published dosimetric and clinical evidence supporting the use of proton therapy for the treatment of cancers in the gastrointestinal tract, such as the stomach, pancreas, hepatobiliary system, rectum, and anal canal. Next, it discusses the benefits of proton therapy in the delivery of reirradiation for recurrent or second primary tumors in a previously irradiated field. It then discusses the potential challenges of using proton therapy for the treatment of gastrointestinal malignancies and finally discusses future directions, including currently ongoing clinical trials.
| Original language | English (US) |
|---|---|
| Title of host publication | Proton Therapy |
| Subtitle of host publication | Indications, Techniques and Outcomes |
| Publisher | Elsevier |
| Pages | 135-144.e6 |
| ISBN (Electronic) | 9780323733496 |
| ISBN (Print) | 9780323733502 |
| DOIs | |
| State | Published - Jan 1 2020 |
Keywords
- anal cancer
- clinical outcomes
- dosimetric benefits
- gastric cancer
- gastrointestinal malignancies
- hepatobiliary cancer
- pancreatic cancer
- proton therapy
- rectal cancer
- toxicity reduction
ASJC Scopus subject areas
- General Medicine