Generalized necrobiotic xanthogranuloma successfully treated with lenalidomide

Sirunya Silapunt, Susan Y. Chon

Research output: Contribution to journalArticlepeer-review

24 Scopus citations

Abstract

Necrobiotic xanthogranuloma (NXG) presents a therapeutic challenge to clinicians. Generalized NXG has limited treatment options. A patient presented to the authors with generalized NXG associated with monoclonal gammopathy of unknown significance (MGUS), a plasma cell dyscrasia considered to be a precursor to multiple myeloma. The patient was treated with lenalidomide, a derivative of thalidomide with efficacy in treatment of multiple myeloma. Resolution of paraproteinemia was associated with resolution of NXG.

Original languageEnglish (US)
Pages (from-to)273-276
Number of pages4
JournalJournal of Drugs in Dermatology
Volume9
Issue number3
StatePublished - Mar 2010

ASJC Scopus subject areas

  • Dermatology

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