@article{589894f7d7ba493eb40c7fbf3e4f8df2,
title = "Genetic Influences on Receptive Joint Attention in Chimpanzees (Pan troglodytes)",
abstract = "Despite their genetic similarity to humans, our understanding of the role of genes on cognitive traits in chimpanzees remains virtually unexplored. Here, we examined the relationship between genetic variation in the arginine vasopressin V1a receptor gene (AVPR1A) and social cognition in chimpanzees. Studies have shown that chimpanzees are polymorphic for a deletion in a sequence in the 5′ flanking region of the AVPR1A, DupB, which contains the variable RS3 repetitive element, which has been associated with variation in social behavior in humans. Results revealed that performance on the social cognition task was significantly heritable. Furthermore, males with one DupB + allele performed significantly better and were more responsive to socio-communicative cues than males homozygous for the DupB- deletion. Performance on a non-social cognition task was not associated with the AVPR1A genotype. The collective findings show that AVPR1A polymorphisms are associated with individual differences in performance on a receptive joint attention task in chimpanzees.",
author = "Hopkins, {William D.} and Keebaugh, {Alaine C.} and Reamer, {Lisa A.} and Jennifer Schaeffer and Schapiro, {Steven J.} and Young, {Larry J.}",
note = "Funding Information: This research was supported by NIH grants MH-92923, NS-42867, NS-73134,HD-60563 to WDH, MH064692 and MH56897 to L.J.Y. Cooperative Agreement RR-15090 to M.D. Funding Information: Anderson Cancer Center, and National Center for Research Resources P51RR165 to YNPRC, which is currently supported by the Office of Research Infrastructure Programs/ OD P51OD11132). We would like to thank Yerkes National Primate Research Center and the University of Texas MD Anderson Cancer Center and their respective veterinary and care staffs for assistance in blood collection. American Psychological Association guidelines for the treatment of animals were followed during all aspects of this study. Inquires regarding this paper may be sent to: William D. Hopkins, Neuroscience Institute, Georgia State University, P.O. Box 5030, Atlanta, Georgia 30302-5030. Email: whopkins4@gsu.edu or whopkin@emory.edu.",
year = "2014",
month = jan,
day = "20",
doi = "10.1038/srep03774",
language = "English (US)",
volume = "4",
journal = "Scientific reports",
issn = "2045-2322",
publisher = "Nature Publishing Group",
}