Genetic risk and gynecologic cancers

Laura L. Holman; Karen H. Lu

doi:10.1016/j.hoc.2011.11.003

Genetic risk and gynecologic cancers

Laura L. Holman, Karen H. Lu

Gynecological Oncology & Reproductive Medicine

Research output: Contribution to journal › Review article › peer-review

4 Scopus citations

Abstract

Hereditary cancer syndromes are responsible for 5% of endometrial cancers and 10% of ovarian cancers. Hereditary breast and ovarian cancer syndrome and Lynch syndrome account for most of these inherited cases. Significant advances have been made in the identification and management of women with these syndromes. In addition, recent advances have highlighted the prognostic and therapeutic implications for women with gynecologic cancers and inherited cancer syndromes.

Original language	English (US)
Pages (from-to)	13-29
Number of pages	17
Journal	Hematology/Oncology Clinics of North America
Volume	26
Issue number	1
DOIs	https://doi.org/10.1016/j.hoc.2011.11.003
State	Published - Feb 2012

Keywords

BRCA
Genetic
Gynecologic cancer
Lynch syndrome

ASJC Scopus subject areas

Hematology
Oncology

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10.1016/j.hoc.2011.11.003

Cite this

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abstract = "Hereditary cancer syndromes are responsible for 5% of endometrial cancers and 10% of ovarian cancers. Hereditary breast and ovarian cancer syndrome and Lynch syndrome account for most of these inherited cases. Significant advances have been made in the identification and management of women with these syndromes. In addition, recent advances have highlighted the prognostic and therapeutic implications for women with gynecologic cancers and inherited cancer syndromes.",

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AU - Lu, Karen H.

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AB - Hereditary cancer syndromes are responsible for 5% of endometrial cancers and 10% of ovarian cancers. Hereditary breast and ovarian cancer syndrome and Lynch syndrome account for most of these inherited cases. Significant advances have been made in the identification and management of women with these syndromes. In addition, recent advances have highlighted the prognostic and therapeutic implications for women with gynecologic cancers and inherited cancer syndromes.

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KW - Genetic

KW - Gynecologic cancer

KW - Lynch syndrome

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ER -

Genetic risk and gynecologic cancers

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

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