Abstract
We herein propose that specific chromosomal aberrations associated with specific neoplasms are not necessarily inherited as a constitutional trait. High-risk individuals may have a tendency to undergo specific somatic mutations or chromosomal rearrangements at a relatively low frequency in all tissues as mosaicism. This may potentiate the development of specific somatic cancers. Our hypothesis may be applicable to both hereditary and sporadic types of neoplasms.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 17-19 |
| Number of pages | 3 |
| Journal | Anticancer research |
| Volume | 9 |
| Issue number | 1 |
| State | Published - 1989 |
ASJC Scopus subject areas
- Oncology
- Cancer Research