Genetics of pancreatic cancer and implications for therapy

Priya Bhosale; Veronica Cox; Silvana Faria; Sanaz Javadi; Chitra Viswanathan; Eugene Koay; Eric Tamm

doi:10.1007/s00261-017-1394-y

Genetics of pancreatic cancer and implications for therapy

Priya Bhosale, Veronica Cox, Silvana Faria, Sanaz Javadi, Chitra Viswanathan, Eugene Koay, Eric Tamm

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Pancreatic cancer is a highly lethal disease with a dismal 5-year prognosis. Knowledge of its genetics may help in identifying new methods for patient screening, and cancer treatment. In this review, we will describe the most common mutations responsible for the genesis of pancreatic cancer and their impact on screening, patterns of disease progression, and therapy.

Original language	English (US)
Pages (from-to)	404-414
Number of pages	11
Journal	Abdominal Radiology
Volume	43
Issue number	2
DOIs	https://doi.org/10.1007/s00261-017-1394-y
State	Published - Feb 1 2018

Keywords

Genomics
Imaging
Mutations
Pancreatic cancer

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Radiology Nuclear Medicine and imaging
Gastroenterology
Urology

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10.1007/s00261-017-1394-y

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AU - Cox, Veronica

AU - Faria, Silvana

AU - Javadi, Sanaz

AU - Viswanathan, Chitra

AU - Koay, Eugene

AU - Tamm, Eric

N1 - Funding Information: Acknowledgments The University of Texas is supported in part by the National Institutes of Health through the Cancer Center Support Grant, P30CA016672. Publisher Copyright: © 2017, Springer Science+Business Media, LLC, part of Springer Nature.

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N2 - Pancreatic cancer is a highly lethal disease with a dismal 5-year prognosis. Knowledge of its genetics may help in identifying new methods for patient screening, and cancer treatment. In this review, we will describe the most common mutations responsible for the genesis of pancreatic cancer and their impact on screening, patterns of disease progression, and therapy.

AB - Pancreatic cancer is a highly lethal disease with a dismal 5-year prognosis. Knowledge of its genetics may help in identifying new methods for patient screening, and cancer treatment. In this review, we will describe the most common mutations responsible for the genesis of pancreatic cancer and their impact on screening, patterns of disease progression, and therapy.

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KW - Imaging

KW - Mutations

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Genetics of pancreatic cancer and implications for therapy

Abstract

Keywords

ASJC Scopus subject areas

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