Abstract
An adult female rhesus monkey that had received 44.0 Gy of cobalt 60 radiation to 8 cm of the cervical and upper thoracic spinal cord approximately 2.8 years postirradiation developed a sudden onset of self-mutilation and loss of function of the right arm followed progressively by loss of function of the left arm and terminally bilateral paresis of the legs. Histopathologic examination of the cervical spinal cord revealed a glioblastoma multiforme that extended from the cervical medullary junction to the sixth cervical vertebrae. Because of the infrequent occurrence of spontaneous neoplasia in rhesus monkeys and the location in the radiation field, the glioblastoma is believed to be radiation induced.
Original language | English (US) |
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Pages (from-to) | 140-145 |
Number of pages | 6 |
Journal | Journal of medical primatology |
Volume | 25 |
Issue number | 2 |
DOIs | |
State | Published - Apr 1996 |
Keywords
- Glioblastoma
- Macaca mulatta
- Primates
- Radiotherapy
- Rhesus
ASJC Scopus subject areas
- Animal Science and Zoology
- General Veterinary