TY - JOUR
T1 - Granuloma Annulare
T2 - An Updated Review of Epidemiology, Pathogenesis, and Treatment Options
AU - Joshi, Tejas P.
AU - Duvic, Madeleine
N1 - Publisher Copyright:
© 2021, The Author(s), under exclusive licence to Springer Nature Switzerland AG.
PY - 2022/1
Y1 - 2022/1
N2 - Granuloma annulare (GA) is an inflammatory granulomatous skin disease that can be localized (localized GA) or disseminated (generalized GA), with patch, perforating, and subcutaneous subtypes being less common variants of this benign condition. Recently, new research has emerged that further elucidates GA epidemiology and etiopathogenesis; importantly, new therapeutic options for GA have also been described, although there remains a paucity of randomized controlled studies. In this review, we summarize recent updates on GA epidemiology and etiopathogenesis and offer an updated review of the therapeutic options for GA currently reported in the literature. We hope that the current review galvanizes randomized controlled studies that will in turn help lead to the recommendation of evidence-based treatments for GA.
AB - Granuloma annulare (GA) is an inflammatory granulomatous skin disease that can be localized (localized GA) or disseminated (generalized GA), with patch, perforating, and subcutaneous subtypes being less common variants of this benign condition. Recently, new research has emerged that further elucidates GA epidemiology and etiopathogenesis; importantly, new therapeutic options for GA have also been described, although there remains a paucity of randomized controlled studies. In this review, we summarize recent updates on GA epidemiology and etiopathogenesis and offer an updated review of the therapeutic options for GA currently reported in the literature. We hope that the current review galvanizes randomized controlled studies that will in turn help lead to the recommendation of evidence-based treatments for GA.
UR - http://www.scopus.com/inward/record.url?scp=85114406816&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85114406816&partnerID=8YFLogxK
U2 - 10.1007/s40257-021-00636-1
DO - 10.1007/s40257-021-00636-1
M3 - Review article
C2 - 34495491
AN - SCOPUS:85114406816
SN - 1175-0561
VL - 23
SP - 37
EP - 50
JO - American Journal of Clinical Dermatology
JF - American Journal of Clinical Dermatology
IS - 1
ER -