Haematological malignancies: At the forefront of immunotherapeutic innovation

Pavan Bachireddy; Ute E. Burkhardt; Mohini Rajasagi; Catherine J. Wu

doi:10.1038/nrc3907

Haematological malignancies: At the forefront of immunotherapeutic innovation

Pavan Bachireddy, Ute E. Burkhardt, Mohini Rajasagi, Catherine J. Wu

Research output: Contribution to journal › Review article › peer-review

61 Scopus citations

Abstract

The recent successes of cancer immunotherapies have stimulated interest in the potential widespread application of these approaches; haematological malignancies have provided both initial proofs of concept and an informative testing ground for various immune-based therapeutics. The immune-cell origin of many of the blood malignancies provides a unique opportunity both to understand the mechanisms of cancer immune responsiveness and immune evasion, and to exploit these mechanisms for therapeutic purposes.

Original language	English (US)
Pages (from-to)	201-215
Number of pages	15
Journal	Nature Reviews Cancer
Volume	15
Issue number	4
DOIs	https://doi.org/10.1038/nrc3907
State	Published - Apr 27 2015
Externally published	Yes

ASJC Scopus subject areas

Oncology
Cancer Research

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10.1038/nrc3907

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Haematological malignancies: At the forefront of immunotherapeutic innovation

Abstract

ASJC Scopus subject areas

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