Head and neck

Steven Jay Frank; G. Brandon Gunn

doi:10.1016/B978-0-323-73349-6.00022-4

Head and neck

Steven Jay Frank, G. Brandon Gunn

Radiation Oncology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Advances in treatment planning and delivery of proton therapy, namely, active (spot) scanning intensity-modulated proton therapy, have allowed safer and more effective treatment for even the most complex head and neck cancer (HNC) cases. This chapter reviews the dosimetric advantages of proton therapy in terms of critical organ protection and normal tissue sparing, the encouraging clinical outcomes for various head and neck tumor subsites in terms of both disease control and toxicity reduction, the favorable results compared with photon-based approaches, and ongoing prospective studies of proton therapy for HNC, with illustrative case studies provided.

Original language	English (US)
Title of host publication	Proton Therapy
Subtitle of host publication	Indications, Techniques and Outcomes
Publisher	Elsevier
Pages	161-179
Number of pages	19
ISBN (Electronic)	9780323733496
ISBN (Print)	9780323733502
DOIs	https://doi.org/10.1016/B978-0-323-73349-6.00022-4
State	Published - Jan 1 2020

Keywords

base of skull
eye sparing
intensity-modulated proton therapy
nasal cavity
nasopharynx
oropharynx
paranasal sinus
periorbital
quality of life
reirradiation
salivary gland
toxicity reduction

ASJC Scopus subject areas

General Medicine

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10.1016/B978-0-323-73349-6.00022-4

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title = "Head and neck",

abstract = "Advances in treatment planning and delivery of proton therapy, namely, active (spot) scanning intensity-modulated proton therapy, have allowed safer and more effective treatment for even the most complex head and neck cancer (HNC) cases. This chapter reviews the dosimetric advantages of proton therapy in terms of critical organ protection and normal tissue sparing, the encouraging clinical outcomes for various head and neck tumor subsites in terms of both disease control and toxicity reduction, the favorable results compared with photon-based approaches, and ongoing prospective studies of proton therapy for HNC, with illustrative case studies provided.",

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AU - Gunn, G. Brandon

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AB - Advances in treatment planning and delivery of proton therapy, namely, active (spot) scanning intensity-modulated proton therapy, have allowed safer and more effective treatment for even the most complex head and neck cancer (HNC) cases. This chapter reviews the dosimetric advantages of proton therapy in terms of critical organ protection and normal tissue sparing, the encouraging clinical outcomes for various head and neck tumor subsites in terms of both disease control and toxicity reduction, the favorable results compared with photon-based approaches, and ongoing prospective studies of proton therapy for HNC, with illustrative case studies provided.

KW - base of skull

KW - eye sparing

KW - intensity-modulated proton therapy

KW - nasal cavity

KW - nasopharynx

KW - oropharynx

KW - paranasal sinus

KW - periorbital

KW - quality of life

KW - reirradiation

KW - salivary gland

KW - toxicity reduction

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EP - 179

BT - Proton Therapy

PB - Elsevier

ER -

Head and neck

Abstract

Keywords

ASJC Scopus subject areas

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