Heterogeneous planning for homogeneous protocols

Chris Brooks; George Starkschall; Robin Famiglietti; James Cox; Steven Frank; Ritsuko Komaki; Zhongxing Liao; Craig Stevens; Kenneth Forster

doi:10.1016/j.meddos.2004.03.006

Heterogeneous planning for homogeneous protocols

Chris Brooks, George Starkschall, Robin Famiglietti, James Cox, Steven Frank, Ritsuko Komaki, Zhongxing Liao, Craig Stevens, Kenneth Forster

Radiation Oncology

Research output: Contribution to journal › Article › peer-review

Abstract

Clinical trials often require homogeneous treatment plans. Many institutions, however, have begun using heterogeneous plans. Is it possible to satisfy the requirements of such a protocol while achieving the superior accuracy of heterogeneous treatment planning? At the University of Texas M. D. Anderson Cancer Center, we currently use conformal treatment planning with heterogeneities for thoracic cancers. This paper describes a procedure that has been developed to satisfy the requirements of a homogeneous protocol, such as RTOG 98-01 (A Phase III Study of Amifostine mucosal protection), while maintaining accuracy in treatment planning.

Original language	English (US)
Pages (from-to)	80-84
Number of pages	5
Journal	Medical Dosimetry
Volume	29
Issue number	2
DOIs	https://doi.org/10.1016/j.meddos.2004.03.006
State	Published - Jun 2004

Keywords

Clinical trials
Heterogeneity corrections
Homogeneous protocols
Treatment planning

ASJC Scopus subject areas

Radiological and Ultrasound Technology
Oncology
Radiology Nuclear Medicine and imaging

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10.1016/j.meddos.2004.03.006

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AU - Brooks, Chris

AU - Starkschall, George

AU - Famiglietti, Robin

AU - Cox, James

AU - Frank, Steven

AU - Komaki, Ritsuko

AU - Liao, Zhongxing

AU - Stevens, Craig

AU - Forster, Kenneth

PY - 2004/6

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AB - Clinical trials often require homogeneous treatment plans. Many institutions, however, have begun using heterogeneous plans. Is it possible to satisfy the requirements of such a protocol while achieving the superior accuracy of heterogeneous treatment planning? At the University of Texas M. D. Anderson Cancer Center, we currently use conformal treatment planning with heterogeneities for thoracic cancers. This paper describes a procedure that has been developed to satisfy the requirements of a homogeneous protocol, such as RTOG 98-01 (A Phase III Study of Amifostine mucosal protection), while maintaining accuracy in treatment planning.

KW - Clinical trials

KW - Heterogeneity corrections

KW - Homogeneous protocols

KW - Treatment planning

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Heterogeneous planning for homogeneous protocols

Abstract

Keywords

ASJC Scopus subject areas

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