High grade neuroendocrine carcinoma of the cervix

Gloria Salvo; Preetha Ramalingam; Michael Frumovitz

doi:10.1016/B978-0-323-82938-0.00014-8

High grade neuroendocrine carcinoma of the cervix

Gloria Salvo, Preetha Ramalingam, Michael Frumovitz

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

High grade neuroendocrine carcinoma (NEC) of the cervix consists of small cell, large cell, and undifferentiated NEC. This subtype accounts for only 1%–2% of all cervical cancer cases. Unlike in patients with the more common subtypes of squamous cell and adenocarcinoma, women with high grade NEC have a higher risk of metastatic disease at diagnosis, higher recurrence rates, and decreased survivals. Treatments for newly diagnosed disease often consist of surgery, radiation, and/or chemotherapy. Treatment for recurrence is exceedingly limited with few active agents.

Original language	English (US)
Title of host publication	Diagnosis and Treatment of Rare Gynecologic Cancers
Publisher	Elsevier
Pages	235-252
Number of pages	18
ISBN (Electronic)	9780323829380
ISBN (Print)	9780323829397
DOIs	https://doi.org/10.1016/B978-0-323-82938-0.00014-8
State	Published - Jan 1 2023

Keywords

Chemotherapy
Chromogranin
High grade neuroendocrine cervical cancer
Large cell cervical cancer
Pelvic lymphadenectomy
Radiation therapy
Radical hysterectomy
Small cell cervical cancer
Surgery
Synaptophysin

ASJC Scopus subject areas

General Medicine

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10.1016/B978-0-323-82938-0.00014-8

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title = "High grade neuroendocrine carcinoma of the cervix",

abstract = "High grade neuroendocrine carcinoma (NEC) of the cervix consists of small cell, large cell, and undifferentiated NEC. This subtype accounts for only 1%–2% of all cervical cancer cases. Unlike in patients with the more common subtypes of squamous cell and adenocarcinoma, women with high grade NEC have a higher risk of metastatic disease at diagnosis, higher recurrence rates, and decreased survivals. Treatments for newly diagnosed disease often consist of surgery, radiation, and/or chemotherapy. Treatment for recurrence is exceedingly limited with few active agents.",

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AU - Ramalingam, Preetha

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N2 - High grade neuroendocrine carcinoma (NEC) of the cervix consists of small cell, large cell, and undifferentiated NEC. This subtype accounts for only 1%–2% of all cervical cancer cases. Unlike in patients with the more common subtypes of squamous cell and adenocarcinoma, women with high grade NEC have a higher risk of metastatic disease at diagnosis, higher recurrence rates, and decreased survivals. Treatments for newly diagnosed disease often consist of surgery, radiation, and/or chemotherapy. Treatment for recurrence is exceedingly limited with few active agents.

AB - High grade neuroendocrine carcinoma (NEC) of the cervix consists of small cell, large cell, and undifferentiated NEC. This subtype accounts for only 1%–2% of all cervical cancer cases. Unlike in patients with the more common subtypes of squamous cell and adenocarcinoma, women with high grade NEC have a higher risk of metastatic disease at diagnosis, higher recurrence rates, and decreased survivals. Treatments for newly diagnosed disease often consist of surgery, radiation, and/or chemotherapy. Treatment for recurrence is exceedingly limited with few active agents.

KW - Chemotherapy

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KW - High grade neuroendocrine cervical cancer

KW - Large cell cervical cancer

KW - Pelvic lymphadenectomy

KW - Radiation therapy

KW - Radical hysterectomy

KW - Small cell cervical cancer

KW - Surgery

KW - Synaptophysin

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BT - Diagnosis and Treatment of Rare Gynecologic Cancers

PB - Elsevier

ER -

High grade neuroendocrine carcinoma of the cervix

Abstract

Keywords

ASJC Scopus subject areas

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