High incident fluence and long pulse laser irradiation in conjunction with cryogen spray cooling: An Ex-Vivo study

T. Dai, J. W. Tunnell, B. M. Pikkula, D. W. Chang, B. Anvari

Research output: Contribution to journalConference articlepeer-review

Abstract

We have investigated the utilization of high incident fluence, long pulse laser irradiation in conjunction with cryogen spray cooling (CSC) on ex-vivo human skin. Abdominal skin samples of different types (Fitzpatrick type I-VI) were obtained from patients undergoing the trans-rectus myocutaneoues flap procedures. Each skin type was irradiated with a Candela Vbeam™ laser (wavelength λ-595 nm) at incident dosages of D0=6, 10, 15, 20 J/cm2, pulse durations of τlaser=1.5, 10, 40 ms, without and with CSC. Preliminary results indicate that lightly pigmented skins can sustain higher incident fluence levels than those currently used in therapeutic settings. While the incident dosage of the laser pulse remains the same, longer pulse duration can decrease the degree of epidermal thermal injury.

Original languageEnglish (US)
Pages (from-to)2271-2272
Number of pages2
JournalAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume3
StatePublished - 2002
EventProceedings of the 2002 IEEE Engineering in Medicine and Biology 24th Annual Conference and the 2002 Fall Meeting of the Biomedical Engineering Society (BMES / EMBS) - Houston, TX, United States
Duration: Oct 23 2002Oct 26 2002

Keywords

  • Dermatology
  • Laser therapy
  • Port wine stain
  • Selective photothermolysis

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

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