@inbook{04cb247ac0234507aad500f4f36e4470,
title = "High-resolution microendoscope for the detection of cervical neoplasia",
abstract = "Cervical cancer causes 275,000 deaths each year with 85 % of these deaths occurring in the developing world. One of the primary reasons for the concentration of deaths in developing countries is a lack of effective screening methods suited for the infrastructure of these countries. In order to address this need, we have developed a high-resolution microendoscope (HRME). The HRME is a fiber-based fluorescence microscope with subcellular resolution. Using the vital stain proflavine, we are able to image cell nuclei in vivo and evaluate metrics such as nuclear-to-cytoplasmic ratio, critical to identifying precancerous epithelial regions. In this chapter, we detail the materials and methods necessary to build this system from commercially available parts.",
keywords = "Cancer detection, High resolution imaging, Low-resource settings",
author = "Grant, {Benjamin D.} and Schwarz, {Richard A.} and Timothy Quang and Schmeler, {Kathleen M.} and Rebecca Richards-Kortum",
note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media New York 2015. All rights are reserved. All rights are reserved.",
year = "2015",
month = jan,
day = "27",
doi = "10.1007/978-1-4939-2172-0_28",
language = "English (US)",
isbn = "9781493921713",
volume = "1256",
series = "Methods in Molecular Biology",
publisher = "Springer New York",
pages = "421--434",
booktitle = "Mobile Health Technologies",
}