Hipotireoidismo subclínico na gravidez

Subclinical hypothyroidism is defined as an elevated thyroid-stimulating hormone (TSH) level with a normal circulating thyroxine (free T4). When it occurs during the gestation, it can result in obstetrical complications and fetal neurological defects if it will not be treated adequate and precociously. Currently, many controversies regarding the diagnosis of this disorder exist, particularly on the group of pregnant women that would have to be submitted to the selection tests. Recommendation for evaluation of the thyroid function in all does not exist for pregnant women, only for the considered patients of high risk. In this group, they are enclosed pregnant women with familiar or personal history of thyroid illnesses, or even other auto-immune illnesses, beyond symptoms or physical founds suggestive of dysfunction of the gland. It is important to stand out that, once obtained the diagnosis of Subclinical hypothyroidism in pregnant woman, must be instituted adjusted treatment, in view of the possible deleterious effect on the neuropsychomotor development of the fetus. In this article the authors aim to carry out an update on this issue focusing in the main impact of subclinical hypothyroidism on the developing fetus and its implications for diagnosis, treatment and screening.