Human-Animal Chimeras in Biomedical Research

Richard R. Behringer

doi:10.1016/j.stem.2007.07.021

Human-Animal Chimeras in Biomedical Research

Richard R. Behringer

Genetics

Research output: Contribution to journal › Short survey › peer-review

53 Scopus citations

Abstract

Chimeras are individuals with tissues derived from more than one zygote. Interspecific chimeras have tissues derived from different species. The biological consequences of human-animal chimeras have become an issue of ethical debate. Ironically, human-animal chimeras with human blood, neurons, germ cells, and other tissues have been generated for decades. This has facilitated human biological studies and therapeutic strategies for disease.

Original language	English (US)
Pages (from-to)	259-262
Number of pages	4
Journal	Cell Stem Cell
Volume	1
Issue number	3
DOIs	https://doi.org/10.1016/j.stem.2007.07.021
State	Published - Sep 13 2007

ASJC Scopus subject areas

Molecular Medicine
Genetics
Cell Biology

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10.1016/j.stem.2007.07.021

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title = "Human-Animal Chimeras in Biomedical Research",

abstract = "Chimeras are individuals with tissues derived from more than one zygote. Interspecific chimeras have tissues derived from different species. The biological consequences of human-animal chimeras have become an issue of ethical debate. Ironically, human-animal chimeras with human blood, neurons, germ cells, and other tissues have been generated for decades. This has facilitated human biological studies and therapeutic strategies for disease.",

author = "Behringer, {Richard R.}",

note = "Funding Information: I am grateful to Gabriel Gonzalez for assistance. I apologize for not citing publications because of formatting restrictions. This work was supported by National Institutes of Health grant HD30284 and the Ben F. Love Endowment.",

year = "2007",

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doi = "10.1016/j.stem.2007.07.021",

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AU - Behringer, Richard R.

N1 - Funding Information: I am grateful to Gabriel Gonzalez for assistance. I apologize for not citing publications because of formatting restrictions. This work was supported by National Institutes of Health grant HD30284 and the Ben F. Love Endowment.

PY - 2007/9/13

Y1 - 2007/9/13

N2 - Chimeras are individuals with tissues derived from more than one zygote. Interspecific chimeras have tissues derived from different species. The biological consequences of human-animal chimeras have become an issue of ethical debate. Ironically, human-animal chimeras with human blood, neurons, germ cells, and other tissues have been generated for decades. This has facilitated human biological studies and therapeutic strategies for disease.

AB - Chimeras are individuals with tissues derived from more than one zygote. Interspecific chimeras have tissues derived from different species. The biological consequences of human-animal chimeras have become an issue of ethical debate. Ironically, human-animal chimeras with human blood, neurons, germ cells, and other tissues have been generated for decades. This has facilitated human biological studies and therapeutic strategies for disease.

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DO - 10.1016/j.stem.2007.07.021

M3 - Short survey

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ER -

Human-Animal Chimeras in Biomedical Research

Abstract

ASJC Scopus subject areas

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