Ibrutinib modulates the immunosuppressive CLL microenvironment through STAT3-mediated suppression of regulatory B-cell function and inhibition of the PD-1/PD-L1 pathway

K. Kondo, H. Shaim, P. A. Thompson, J. A. Burger, M. Keating, Z. Estrov, D. Harris, E. Kim, A. Ferrajoli, M. Daher, R. Basar, M. Muftuoglu, N. Imahashi, A. Alsuliman, C. Sobieski, E. Gokdemir, W. Wierda, N. Jain, E. Liu, E. J. ShpallK. Rezvani

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