Identifying aggressive forms of endometrioid-type endometrial cancer: New insights into molecular subtyping

Yuexin Liu; Russell R. Broaddus; Wei Zhang

doi:10.1586/14737140.2015.992420

Identifying aggressive forms of endometrioid-type endometrial cancer: New insights into molecular subtyping

Yuexin Liu, Russell R. Broaddus, Wei Zhang

Pathology

Research output: Contribution to journal › Review article › peer-review

9 Scopus citations

Abstract

Clinical heterogeneity represents a great challenge for cancer therapeutics. Molecular classification of patients into different subtypes based on genetic or epigenetic characteristics has the potential to revolutionize the clinical care and mechanistic understanding of a wide spectrum of cancers, including endometrial carcinoma, the most common gynecological cancer affecting women.

Original language	English (US)
Pages (from-to)	1-3
Number of pages	3
Journal	Expert review of anticancer therapy
Volume	15
Issue number	1
DOIs	https://doi.org/10.1586/14737140.2015.992420
State	Published - Jan 1 2014

Keywords

CTNNB1 mutation
cancer therapeutics
endometrial carcinoma
molecular subtyping
wnt signaling pathway

ASJC Scopus subject areas

Oncology
Pharmacology (medical)

MD Anderson CCSG core facilities

Bioinformatics Shared Resource

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10.1586/14737140.2015.992420

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title = "Identifying aggressive forms of endometrioid-type endometrial cancer: New insights into molecular subtyping",

abstract = "Clinical heterogeneity represents a great challenge for cancer therapeutics. Molecular classification of patients into different subtypes based on genetic or epigenetic characteristics has the potential to revolutionize the clinical care and mechanistic understanding of a wide spectrum of cancers, including endometrial carcinoma, the most common gynecological cancer affecting women.",

keywords = "CTNNB1 mutation, cancer therapeutics, endometrial carcinoma, molecular subtyping, wnt signaling pathway",

author = "Yuexin Liu and Broaddus, {Russell R.} and Wei Zhang",

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year = "2014",

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AU - Broaddus, Russell R.

AU - Zhang, Wei

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PY - 2014/1/1

Y1 - 2014/1/1

N2 - Clinical heterogeneity represents a great challenge for cancer therapeutics. Molecular classification of patients into different subtypes based on genetic or epigenetic characteristics has the potential to revolutionize the clinical care and mechanistic understanding of a wide spectrum of cancers, including endometrial carcinoma, the most common gynecological cancer affecting women.

AB - Clinical heterogeneity represents a great challenge for cancer therapeutics. Molecular classification of patients into different subtypes based on genetic or epigenetic characteristics has the potential to revolutionize the clinical care and mechanistic understanding of a wide spectrum of cancers, including endometrial carcinoma, the most common gynecological cancer affecting women.

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KW - cancer therapeutics

KW - endometrial carcinoma

KW - molecular subtyping

KW - wnt signaling pathway

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Identifying aggressive forms of endometrioid-type endometrial cancer: New insights into molecular subtyping

Abstract

Keywords

ASJC Scopus subject areas

MD Anderson CCSG core facilities

Access to Document

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