TY - GEN
T1 - Image-guided thermochemical ablation
T2 - 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
AU - Cressman, Erik N.K.
N1 - Copyright:
Copyright 2018 Elsevier B.V., All rights reserved.
PY - 2009
Y1 - 2009
N2 - Purpose: To test thermochemical ablation for potential as a new method to coagulate tissue and create a prototype device for administration. Materials and Methods: Reactions of either HCl or acetic acid and either NH4OH or NaOH were run in triplicate in a gel phantom as a simple calorimeter. Data were recorded over a period of 5 minutes using concentrations from 1-12M in the case of HCl and NH4OH. Comparison reactions were run at 11M using each acid reacted with each base. Two early device prototypes were devised using readily available components. Results: Maximum temperature rise was nearly instantaneous and was observed to peak with the 12M solutions at 106°C. The maximum temperatures in the 11M comparisons were seen with the strong acid HCl paired with the strong base NaOH. The lowest temperatures were seen with the weak acid acetic acid paired with the weak base NH4OH. Conclusion: Thermochemical ablation reactions can release adequate amounts of heat energy to cause tissue ablation.
AB - Purpose: To test thermochemical ablation for potential as a new method to coagulate tissue and create a prototype device for administration. Materials and Methods: Reactions of either HCl or acetic acid and either NH4OH or NaOH were run in triplicate in a gel phantom as a simple calorimeter. Data were recorded over a period of 5 minutes using concentrations from 1-12M in the case of HCl and NH4OH. Comparison reactions were run at 11M using each acid reacted with each base. Two early device prototypes were devised using readily available components. Results: Maximum temperature rise was nearly instantaneous and was observed to peak with the 12M solutions at 106°C. The maximum temperatures in the 11M comparisons were seen with the strong acid HCl paired with the strong base NaOH. The lowest temperatures were seen with the weak acid acetic acid paired with the weak base NH4OH. Conclusion: Thermochemical ablation reactions can release adequate amounts of heat energy to cause tissue ablation.
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U2 - 10.1109/IEMBS.2009.5333503
DO - 10.1109/IEMBS.2009.5333503
M3 - Conference contribution
C2 - 19964105
AN - SCOPUS:77950986715
SN - 9781424432967
T3 - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society: Engineering the Future of Biomedicine, EMBC 2009
SP - 4291
EP - 4294
BT - Proceedings of the 31st Annual International Conference of the IEEE Engineering in Medicine and Biology Society
PB - IEEE Computer Society
Y2 - 2 September 2009 through 6 September 2009
ER -