TY - JOUR
T1 - Image improvement and design optimization of the time-of-flight PET
AU - Wong, W. H.
AU - Mullani, N. A.
AU - Philippe, E. A.
AU - Hartz, R.
AU - Gould, K. L.
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 1983
Y1 - 1983
N2 - Positron emission tomography (PET) with the added time-of-flight information has been shown to provide a better reconstructed image over conventional positron tomography. This improvement depends on the size of the object being imaged, the intrinsic resolution of the detector, and the time-of-flight resolution. Moreover, the signal-to-noise ratio of PET image is related not only to the total number of counts in the image but also to the event-locating uncertainties, the reconstruction filter function, and the recovered resolution in the image. The study provides a physical explanation for, and description of, the improvement in signal-to-noise ratio of a reconstructed image as a function of the crucial design parameters: time-to-flight timing resolution, intrinsic detector resolution, object size, and reconstructed image resolution.
AB - Positron emission tomography (PET) with the added time-of-flight information has been shown to provide a better reconstructed image over conventional positron tomography. This improvement depends on the size of the object being imaged, the intrinsic resolution of the detector, and the time-of-flight resolution. Moreover, the signal-to-noise ratio of PET image is related not only to the total number of counts in the image but also to the event-locating uncertainties, the reconstruction filter function, and the recovered resolution in the image. The study provides a physical explanation for, and description of, the improvement in signal-to-noise ratio of a reconstructed image as a function of the crucial design parameters: time-to-flight timing resolution, intrinsic detector resolution, object size, and reconstructed image resolution.
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M3 - Article
C2 - 6600276
AN - SCOPUS:0020662189
SN - 0161-5505
VL - 24
SP - 52
EP - 60
JO - Journal of Nuclear Medicine
JF - Journal of Nuclear Medicine
IS - 1
ER -