Immunotherapy combined with high- and low-dose radiation to all sites leads to complete clearance of disease in a patient with metastatic vaginal melanoma

Duygu Sezen, Roshal R. Patel, Christine Tang, Michaela Onstad, Priyadharsini Nagarajan, Sapna P. Patel, James W. Welsh, Lilie L. Lin

Research output: Contribution to journalArticlepeer-review

Abstract

A 73-year-old woman with metastatic vaginal mucosal melanoma that had progressed on ipilimumab and nivolumab experienced clinical and radiographic complete response to dual checkpoint inhibitor immunotherapy given in combination with high-dose plus low-dose radiation. General characteristics and treatment options in this disease are highlighted.

Original languageEnglish (US)
Pages (from-to)645-652
Number of pages8
JournalGynecologic oncology
Volume161
Issue number3
DOIs
StatePublished - Jun 2021

Keywords

  • Abscopal effect
  • Immunotherapy
  • Low dose radiation
  • Vaginal mucosal melanoma

ASJC Scopus subject areas

  • Oncology
  • Obstetrics and Gynecology

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