Impact of lung block shape on cardiac dose for total body irradiation

Mallory C. Glenn; Kent Wallner; Samuel M.H. Luk; Ralph Ermoian; Yolanda D. Tseng; Mark Phillips; Minsun Kim

doi:10.1016/j.phro.2022.01.004

Impact of lung block shape on cardiac dose for total body irradiation

Mallory C. Glenn, Kent Wallner, Samuel M.H. Luk, Ralph Ermoian, Yolanda D. Tseng, Mark Phillips, Minsun Kim

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Evaluating cardiac dose during total body irradiation (TBI) is of increasing interest. A three-dimensional beam model for TBI was commissioned and lung shielding was simulated in a treatment planning system with the cardiac silhouette partially blocked and unblocked. When blocked, the median heart dose decreased by 6% (IQR = 6%) and the median cardiac V12Gy decreased by 27% (IQR = 17%). The median left anterior descending artery dose decreased 20% (IQR = 12%) for blocked cases. Because using partial heart shielding may result in considerable changes in dose to cardiac structures, TBI protocols should explicitly consider lung block design parameters and their potential effects.

Original language	English (US)
Pages (from-to)	30-34
Number of pages	5
Journal	Physics and Imaging in Radiation Oncology
Volume	21
DOIs	https://doi.org/10.1016/j.phro.2022.01.004
State	Published - Jan 2022
Externally published	Yes

Keywords

Blocks
Body
Heart
Oncology
Radiation
Total

ASJC Scopus subject areas

Radiation
Oncology
Radiology Nuclear Medicine and imaging

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10.1016/j.phro.2022.01.004

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title = "Impact of lung block shape on cardiac dose for total body irradiation",

abstract = "Evaluating cardiac dose during total body irradiation (TBI) is of increasing interest. A three-dimensional beam model for TBI was commissioned and lung shielding was simulated in a treatment planning system with the cardiac silhouette partially blocked and unblocked. When blocked, the median heart dose decreased by 6% (IQR = 6%) and the median cardiac V12Gy decreased by 27% (IQR = 17%). The median left anterior descending artery dose decreased 20% (IQR = 12%) for blocked cases. Because using partial heart shielding may result in considerable changes in dose to cardiac structures, TBI protocols should explicitly consider lung block design parameters and their potential effects.",

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AU - Glenn, Mallory C.

AU - Wallner, Kent

AU - Luk, Samuel M.H.

AU - Ermoian, Ralph

AU - Tseng, Yolanda D.

AU - Phillips, Mark

AU - Kim, Minsun

PY - 2022/1

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AB - Evaluating cardiac dose during total body irradiation (TBI) is of increasing interest. A three-dimensional beam model for TBI was commissioned and lung shielding was simulated in a treatment planning system with the cardiac silhouette partially blocked and unblocked. When blocked, the median heart dose decreased by 6% (IQR = 6%) and the median cardiac V12Gy decreased by 27% (IQR = 17%). The median left anterior descending artery dose decreased 20% (IQR = 12%) for blocked cases. Because using partial heart shielding may result in considerable changes in dose to cardiac structures, TBI protocols should explicitly consider lung block design parameters and their potential effects.

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KW - Radiation

KW - Total

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Impact of lung block shape on cardiac dose for total body irradiation

Abstract

Keywords

ASJC Scopus subject areas

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