Improving x-ray fluorescence signal for benchtop polychromatic cone-beam x-ray fluorescence computed tomography by incident x-ray spectrum optimization: A Monte Carlo study

Nivedh Manohar; Bernard L. Jones; Sang Hyun Cho

doi:10.1118/1.4895004

Improving x-ray fluorescence signal for benchtop polychromatic cone-beam x-ray fluorescence computed tomography by incident x-ray spectrum optimization: A Monte Carlo study

Nivedh Manohar, Bernard L. Jones, Sang Hyun Cho

Radiation Physics

Research output: Contribution to journal › Article › peer-review

28 Scopus citations

Abstract

Purpose: To develop an accurate and comprehensive Monte Carlo (MC) model of an experimental benchtop polychromatic cone-beam x-ray fluorescence computed tomography (XFCT) setup and apply this MC model to optimize incident x-ray spectrum for improving production/detection of x-ray fluorescence photons from gold nanoparticles (GNPs).

Original language	English (US)
Article number	101906
Journal	Medical physics
Volume	41
Issue number	10
DOIs	https://doi.org/10.1118/1.4895004
State	Published - Oct 1 2014

Keywords

Monte Carlo method
computed tomography
gold nanoparticles
x-ray fluorescence

ASJC Scopus subject areas

Biophysics
Radiology Nuclear Medicine and imaging

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10.1118/1.4895004

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abstract = "Purpose: To develop an accurate and comprehensive Monte Carlo (MC) model of an experimental benchtop polychromatic cone-beam x-ray fluorescence computed tomography (XFCT) setup and apply this MC model to optimize incident x-ray spectrum for improving production/detection of x-ray fluorescence photons from gold nanoparticles (GNPs).",

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author = "Nivedh Manohar and Jones, {Bernard L.} and Cho, {Sang Hyun}",

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AU - Jones, Bernard L.

AU - Cho, Sang Hyun

PY - 2014/10/1

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N2 - Purpose: To develop an accurate and comprehensive Monte Carlo (MC) model of an experimental benchtop polychromatic cone-beam x-ray fluorescence computed tomography (XFCT) setup and apply this MC model to optimize incident x-ray spectrum for improving production/detection of x-ray fluorescence photons from gold nanoparticles (GNPs).

AB - Purpose: To develop an accurate and comprehensive Monte Carlo (MC) model of an experimental benchtop polychromatic cone-beam x-ray fluorescence computed tomography (XFCT) setup and apply this MC model to optimize incident x-ray spectrum for improving production/detection of x-ray fluorescence photons from gold nanoparticles (GNPs).

KW - Monte Carlo method

KW - computed tomography

KW - gold nanoparticles

KW - x-ray fluorescence

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Improving x-ray fluorescence signal for benchtop polychromatic cone-beam x-ray fluorescence computed tomography by incident x-ray spectrum optimization: A Monte Carlo study

Abstract

Keywords

ASJC Scopus subject areas

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