TY - JOUR
T1 - In vitro susceptibilities of Nocardia species to newer antimicrobial agents
AU - Berkey, P.
AU - Moore, D.
AU - Rolston, K.
PY - 1988
Y1 - 1988
N2 - The in vitro activities of various quinolones, two newer cephalosporins, and imipenem against 23 strains of Nocardia asteroides, 4 strains of Nocardia brasiliensis, and 4 strains of Nocardia caviae were determined by an agar dilution method. PD-117558, a newer carboxyquinolone, and imipenem were the most active agents tested, inhibiting 90% of N. asteroides isolates at an MIC of 2 μg/ml. Of the 23 strains of N. asteroides, 15 were susceptible to cefpirome and 10 were suceptible to ciprofloxacin. The N. brasiliensis and N. caviae strains were very susceptible to PD-117558 (MIC, ≤ 1 μg/ml), moderately susceptible to ciprofloxacin, and resistant to most of the other tested drugs.
AB - The in vitro activities of various quinolones, two newer cephalosporins, and imipenem against 23 strains of Nocardia asteroides, 4 strains of Nocardia brasiliensis, and 4 strains of Nocardia caviae were determined by an agar dilution method. PD-117558, a newer carboxyquinolone, and imipenem were the most active agents tested, inhibiting 90% of N. asteroides isolates at an MIC of 2 μg/ml. Of the 23 strains of N. asteroides, 15 were susceptible to cefpirome and 10 were suceptible to ciprofloxacin. The N. brasiliensis and N. caviae strains were very susceptible to PD-117558 (MIC, ≤ 1 μg/ml), moderately susceptible to ciprofloxacin, and resistant to most of the other tested drugs.
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U2 - 10.1128/AAC.32.7.1078
DO - 10.1128/AAC.32.7.1078
M3 - Article
C2 - 3190193
AN - SCOPUS:0023784387
SN - 0066-4804
VL - 32
SP - 1078
EP - 1079
JO - Antimicrobial agents and chemotherapy
JF - Antimicrobial agents and chemotherapy
IS - 7
ER -