TY - JOUR
T1 - Incidence of neonatal seizures in Harris County, Texas, 1992-1994
AU - Saliba, Rima M.
AU - Annegers, J. Fred
AU - Waller, D. Kim
AU - Tyson, Jon E.
AU - Mizrahi, Eli M.
N1 - Funding Information:
This study was supported by grant NO1-NS-1-2316 from the National Institute of Neurological Disorders and Stroke. The authors thank the medical records staff at the participating hospitals for their valuable cooperation, and Sharon Coan and Tony Lam for their assistance with data management.
PY - 1999/10/1
Y1 - 1999/10/1
N2 - This study estimated the incidence of clinical neonatal seizures among infants born between 1992 and 1994 in Harris County, Texas, a county with a large and ethnically diverse population. Infants with neonatal seizures were ascertained from four sources: hospital discharge diagnoses, birth certificates, death certificates, and a study of neonatal seizures conducted concurrently with this study at a large tertiary care center in Houston, Texas. There were 207 cases of clinical neonatal seizures among 116,048 live births (an incidence of 1.8 per 1,000 live births). The incidence was highest among infants weighing less than 1,500 g (19/1,000) and decreased as birth weight increased. There was no significant difference in incidence by ethnicity. Twenty-six percent of the seizures (54/207) occurred after the infants had been discharged from the hospital where they were born. The incidence of neonatal seizures in Harris County was lower than the incidence reported recently for Fayette County, Kentucky, for 1985-1989 (3.5/1.000) and for Newfoundland, Canada, for 1990 1995 (2.5/1.000), but was higher than the incidence estimated for Rochester. Minnesota, for 1935-1984 (1/1,000).
AB - This study estimated the incidence of clinical neonatal seizures among infants born between 1992 and 1994 in Harris County, Texas, a county with a large and ethnically diverse population. Infants with neonatal seizures were ascertained from four sources: hospital discharge diagnoses, birth certificates, death certificates, and a study of neonatal seizures conducted concurrently with this study at a large tertiary care center in Houston, Texas. There were 207 cases of clinical neonatal seizures among 116,048 live births (an incidence of 1.8 per 1,000 live births). The incidence was highest among infants weighing less than 1,500 g (19/1,000) and decreased as birth weight increased. There was no significant difference in incidence by ethnicity. Twenty-six percent of the seizures (54/207) occurred after the infants had been discharged from the hospital where they were born. The incidence of neonatal seizures in Harris County was lower than the incidence reported recently for Fayette County, Kentucky, for 1985-1989 (3.5/1.000) and for Newfoundland, Canada, for 1990 1995 (2.5/1.000), but was higher than the incidence estimated for Rochester. Minnesota, for 1935-1984 (1/1,000).
KW - Convulsions
KW - Incidence
KW - Infant, very low birth weight
KW - Neonatal diseases and abnormalities
KW - Seizures
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U2 - 10.1093/oxfordjournals.aje.a010079
DO - 10.1093/oxfordjournals.aje.a010079
M3 - Article
C2 - 10512430
AN - SCOPUS:0033214109
SN - 0002-9262
VL - 150
SP - 763
EP - 769
JO - American journal of epidemiology
JF - American journal of epidemiology
IS - 7
ER -