Increased Granulocyte Collection with the Blood Cell Separator and the Addition of Etiocholanolone and Hydroxyethyl Starch

K. B. McCredie, E. J. Freireich, J. P. Hester, Carlos S. Vallejos

Research output: Contribution to journalArticle

79 Citations (Scopus)

Abstract

A total of 201 leukaphereses have been performed on 73 donors to collect granulocytes for transfusion to infected leukopenic recipients. The pretreatment of the donor with etiocholanolone and the addition of hydroxyethyl starch to the extracorporeal circulation significantly increased the total number of granulocytes collected. Adverse side effects were minimal. The majority of donors underwent the procedure on 13 occasions over a period of eight weeks. Follow‐up donors two or more years later has revealed no long‐term adverse side effects from leukapheresis or from the addition of etiocholanolone and hydroxyethyl starch. 1974 AABB

Original languageEnglish (US)
Pages (from-to)357-364
Number of pages8
JournalTransfusion
Volume14
Issue number4
DOIs
StatePublished - Jan 1 1974

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Etiocholanolone
Leukapheresis
Granulocytes
Starch
Blood Cells
Extracorporeal Circulation

ASJC Scopus subject areas

  • Immunology and Allergy
  • Immunology
  • Hematology

Cite this

Increased Granulocyte Collection with the Blood Cell Separator and the Addition of Etiocholanolone and Hydroxyethyl Starch. / McCredie, K. B.; Freireich, E. J.; Hester, J. P.; Vallejos, Carlos S.

In: Transfusion, Vol. 14, No. 4, 01.01.1974, p. 357-364.

Research output: Contribution to journalArticle

McCredie, K. B. ; Freireich, E. J. ; Hester, J. P. ; Vallejos, Carlos S. / Increased Granulocyte Collection with the Blood Cell Separator and the Addition of Etiocholanolone and Hydroxyethyl Starch. In: Transfusion. 1974 ; Vol. 14, No. 4. pp. 357-364.
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