Increased Granulocyte Collection with the Blood Cell Separator and the Addition of Etiocholanolone and Hydroxyethyl Starch

K. B. McCredie; E. J. Freireich; J. P. Hester; C. Vallejos

doi:10.1111/j.1537-2995.1974.tb04545.x

Increased Granulocyte Collection with the Blood Cell Separator and the Addition of Etiocholanolone and Hydroxyethyl Starch

K. B. McCredie, E. J. Freireich, J. P. Hester, C. Vallejos

Leukemia

Research output: Contribution to journal › Article › peer-review

83 Scopus citations

Abstract

A total of 201 leukaphereses have been performed on 73 donors to collect granulocytes for transfusion to infected leukopenic recipients. The pretreatment of the donor with etiocholanolone and the addition of hydroxyethyl starch to the extracorporeal circulation significantly increased the total number of granulocytes collected. Adverse side effects were minimal. The majority of donors underwent the procedure on 13 occasions over a period of eight weeks. Follow‐up donors two or more years later has revealed no long‐term adverse side effects from leukapheresis or from the addition of etiocholanolone and hydroxyethyl starch. 1974 AABB

Original language	English (US)
Pages (from-to)	357-364
Number of pages	8
Journal	Transfusion
Volume	14
Issue number	4
DOIs	https://doi.org/10.1111/j.1537-2995.1974.tb04545.x
State	Published - 1974

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Hematology

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title = "Increased Granulocyte Collection with the Blood Cell Separator and the Addition of Etiocholanolone and Hydroxyethyl Starch",

abstract = "A total of 201 leukaphereses have been performed on 73 donors to collect granulocytes for transfusion to infected leukopenic recipients. The pretreatment of the donor with etiocholanolone and the addition of hydroxyethyl starch to the extracorporeal circulation significantly increased the total number of granulocytes collected. Adverse side effects were minimal. The majority of donors underwent the procedure on 13 occasions over a period of eight weeks. Follow‐up donors two or more years later has revealed no long‐term adverse side effects from leukapheresis or from the addition of etiocholanolone and hydroxyethyl starch. 1974 AABB",

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AU - McCredie, K. B.

AU - Freireich, E. J.

AU - Hester, J. P.

AU - Vallejos, C.

PY - 1974

Y1 - 1974

N2 - A total of 201 leukaphereses have been performed on 73 donors to collect granulocytes for transfusion to infected leukopenic recipients. The pretreatment of the donor with etiocholanolone and the addition of hydroxyethyl starch to the extracorporeal circulation significantly increased the total number of granulocytes collected. Adverse side effects were minimal. The majority of donors underwent the procedure on 13 occasions over a period of eight weeks. Follow‐up donors two or more years later has revealed no long‐term adverse side effects from leukapheresis or from the addition of etiocholanolone and hydroxyethyl starch. 1974 AABB

AB - A total of 201 leukaphereses have been performed on 73 donors to collect granulocytes for transfusion to infected leukopenic recipients. The pretreatment of the donor with etiocholanolone and the addition of hydroxyethyl starch to the extracorporeal circulation significantly increased the total number of granulocytes collected. Adverse side effects were minimal. The majority of donors underwent the procedure on 13 occasions over a period of eight weeks. Follow‐up donors two or more years later has revealed no long‐term adverse side effects from leukapheresis or from the addition of etiocholanolone and hydroxyethyl starch. 1974 AABB

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Increased Granulocyte Collection with the Blood Cell Separator and the Addition of Etiocholanolone and Hydroxyethyl Starch

Abstract

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