TY - JOUR
T1 - Inflammatory breast cancer
T2 - A review
AU - Jaiyesimi, Ishmael A.
AU - Buzdar, Aman U.
AU - Hortobagyi, Gabriel
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1992
Y1 - 1992
N2 - Purpose: The natural history of inflammatory breast cancer and the recent advances in its management were reviewed. Design: The English medical literature from 1924 to 1990 was reviewed using the Cancerline and Medline retrieval systems, and through a manual review of bibliographies of identified articles. Results: The majority of patients with inflammatory breast cancer treated only with local therapies died 18 to 24 months after diagnosis. A combined modality approach with chemotherapy, surgery, and radiation therapy has improved disease-free and overall survival rates for inflammatory breast cancer. Approximately 35% to 55% of patients treated with combined modality regimens remain disease-free and alive at 5 years. Conclusion: Induction combination chemotherapy administered with radiation therapy, mastectomy, both, or with additional chemotherapy favorably alters the natural history of inflammatory breast cancer. New drug combinations and high-dose chemotherapy with autologous bone marrow support are being evaluated to improve further patient survival.
AB - Purpose: The natural history of inflammatory breast cancer and the recent advances in its management were reviewed. Design: The English medical literature from 1924 to 1990 was reviewed using the Cancerline and Medline retrieval systems, and through a manual review of bibliographies of identified articles. Results: The majority of patients with inflammatory breast cancer treated only with local therapies died 18 to 24 months after diagnosis. A combined modality approach with chemotherapy, surgery, and radiation therapy has improved disease-free and overall survival rates for inflammatory breast cancer. Approximately 35% to 55% of patients treated with combined modality regimens remain disease-free and alive at 5 years. Conclusion: Induction combination chemotherapy administered with radiation therapy, mastectomy, both, or with additional chemotherapy favorably alters the natural history of inflammatory breast cancer. New drug combinations and high-dose chemotherapy with autologous bone marrow support are being evaluated to improve further patient survival.
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U2 - 10.1200/JCO.1992.10.6.1014
DO - 10.1200/JCO.1992.10.6.1014
M3 - Review article
C2 - 1588366
AN - SCOPUS:0026690997
SN - 0732-183X
VL - 10
SP - 1014
EP - 1024
JO - Journal of Clinical Oncology
JF - Journal of Clinical Oncology
IS - 6
ER -