TY - JOUR
T1 - Influence of data display formats on physician investigators' decisions to stop clinical trials
T2 - Prospective trial with repeated measures
AU - Elting, Linda S.
AU - Martin, Charles G.
AU - Cantor, Scott B.
AU - Rubenstein, Edward B.
PY - 1999/6/5
Y1 - 1999/6/5
N2 - Objective. To examine the effect of the method of data display on physician investigators' decisions to stop hypothetical clinical trials for an unplanned statistical analysis. Design. Prospective, mixed model design with variables between subjects and within subjects (repeated measures). Setting. Comprehensive cancer centre. Participants. 34 physicians, stratified by academic rank, who were conducting clinical trials. Interventions. Participants were shown tables, pie charts, bar graphs, and icon displays containing hypothetical data from a clinical trial and were asked to decide whether to continue the trial or stop for an unplanned statistical analysis. Main outcome measure. Percentage of accurate decisions with each type of display. Results. Accuracy of decisions was affected by the type of data display and positive or negative framing of the data. More correct decisions were made with icon displays than with tables, pie charts, and bar graphs (82% v 68%, 56% and 43%, respectively; P = 0.03) and when data were negatively framed rather than positively framed in tables (93% v 47%; P = 0.004). Conclusions. Clinical investigators' decisions can be affected by factors unrelated to the actual data. In the design of clinical trials information systems, careful consideration should be given to the method by which data are framed and displayed in order to reduce the impact of these extraneous factors.
AB - Objective. To examine the effect of the method of data display on physician investigators' decisions to stop hypothetical clinical trials for an unplanned statistical analysis. Design. Prospective, mixed model design with variables between subjects and within subjects (repeated measures). Setting. Comprehensive cancer centre. Participants. 34 physicians, stratified by academic rank, who were conducting clinical trials. Interventions. Participants were shown tables, pie charts, bar graphs, and icon displays containing hypothetical data from a clinical trial and were asked to decide whether to continue the trial or stop for an unplanned statistical analysis. Main outcome measure. Percentage of accurate decisions with each type of display. Results. Accuracy of decisions was affected by the type of data display and positive or negative framing of the data. More correct decisions were made with icon displays than with tables, pie charts, and bar graphs (82% v 68%, 56% and 43%, respectively; P = 0.03) and when data were negatively framed rather than positively framed in tables (93% v 47%; P = 0.004). Conclusions. Clinical investigators' decisions can be affected by factors unrelated to the actual data. In the design of clinical trials information systems, careful consideration should be given to the method by which data are framed and displayed in order to reduce the impact of these extraneous factors.
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U2 - 10.1136/bmj.318.7197.1527
DO - 10.1136/bmj.318.7197.1527
M3 - Article
C2 - 10356010
AN - SCOPUS:0032988978
SN - 0959-8146
VL - 318
SP - 1527
EP - 1531
JO - British Medical Journal
JF - British Medical Journal
IS - 7197
ER -